867035-87-8

Basic information

• Product Name: dimethyl-{2-[3-(1-pyrazin-2-yl-ethyl)-1H-inden-2-yl]-ethyl}-amine
• Synonyms: dimethyl-{2-[3-(1-pyrazin-2-yl-ethyl)-1H-inden-2-yl]-ethyl}-amine
• CAS NO: 867035-87-8
• Molecular Weight: 293.412
• Mol File: 867035-87-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl-{2-[3-(1-pyrazin-2-yl-ethyl)-1H-inden-2-yl]-ethyl}-amine(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl-{2-[3-(1-pyrazin-2-yl-ethyl)-1H-inden-2-yl]-ethyl}-amine(867035-87-8)
• EPA Substance Registry System: dimethyl-{2-[3-(1-pyrazin-2-yl-ethyl)-1H-inden-2-yl]-ethyl}-amine(867035-87-8)

Safety Data

• Hazardous Substances Data: 867035-87-8(Hazardous Substances Data)

Upstream product

• 13925-00-3 2-ethylpyrazine 
• 3409-21-0 2-[2-(dimethylamino)ethyl]indan-1-one 

Relevant articles and documents

Characterization of novel selective H1-antihistamines for clinical evaluation in the treatment of insomnia

Analogues of the known H1-antihistamine R-dimethindene were profiled as potential agents for the treatment of insomnia. Several highly selective compounds were efficacious in rodent sleep models. On the basis of overall profile, indene 1d and benzothiophene 2a had pharmacokinetic properties suitable for evaluation in night time dosing. Compound 2a did not show an in vivo cardiovascular effect from weak hERG channel inhibition.