867062-95-1

Basic information

• Product Name: FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID
• Synonyms: FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID;N-Fmoc-12-amino-4,7,10-trioxadodecanoic acid;FMoc-NH-PEG3-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid;Fmoc-N-amido-PEG3-acid;Fmoc-PEG3- CH2CH2COOH;Fmoc-PEG3-propionic acid;Fmoc-PEG3-OH 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
• CAS NO: 867062-95-1
• Molecular Formula: C₂₄H₂₉NO₇
• Molecular Weight: 443.49
• Mol File: 867062-95-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 651.125 °C at 760 mmHg
• Flash Point: 347.588 °C
• Appearance: /
• Density: 1.230
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C
• Solubility: DMSO (Sparingly), Methanol (Slightly)
• PKA: 4.28±0.10(Predicted)
• CAS DataBase Reference: FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID(867062-95-1)
• EPA Substance Registry System: FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID(867062-95-1)

Safety Data

• Hazardous Substances Data: 867062-95-1(Hazardous Substances Data)

Usage

Description

FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID is a compound that contains an Fmoc-protected amine and a terminal carboxylic acid, connected by a 12-atom linker. The Fmoc group can be deprotected under basic conditions to reveal the free amine, which can then be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators to form a stable amide bond. FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID is useful in the synthesis of various bioconjugates and pharmaceuticals.

Uses

Used in Pharmaceutical Industry:
FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID is used as a building block for the synthesis of pharmaceuticals and bioconjugates. Its Fmoc-protected amine allows for selective deprotection and conjugation to other molecules, while the terminal carboxylic acid can form stable amide bonds with primary amines.
Used in Vaccine Development:
FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID is used as a reactant in the preparation of vaccines. Its ability to form stable amide bonds with primary amines makes it a valuable component in the synthesis of vaccine candidates.
Used in Bioconjugation:
FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID is used as a linker in bioconjugation, allowing for the attachment of various molecules to create new functional materials. Its Fmoc-protected amine and terminal carboxylic acid enable selective conjugation and stable bond formation.

InChI:InChI=1/C24H29NO7/c25-22(16-31-14-13-30-12-11-29-10-9-23(26)27)24(28)32-15-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-8,21-22H,9-16,25H2,(H,26,27)

Upstream product

• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 139115-92-7 tert-butyl 2-(2-(2-hydroxyethoxy)ethoxy)ethylcarbamate 
• 252881-74-6 tert-butyl 3-(2-(2-(2-aminoethoxyl)ethoxy)ethoxy)propanoate 
• 1024602-74-1 tert-butyl 3-(2-{2-[2-(methanesulphonyloxy)ethoxy]ethoxy}ethoxy)propanoate 
• 252881-73-5 tert-Butyl 3-(2-(2-(2-azidoethoxyl)ethoxy)ethoxy)propanoate 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 186020-66-6 3-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester 

Downstream Products

• 1352827-47-4 2,5-dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oate 

Relevant articles and documents

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