86814-29-1Relevant articles and documents
SYNTHESIS OF NEW α-CHLOROACRYL-AMIDES, THIOAMIDES AND AMIDINES FROM SATURATED AMIDES.
Lambert, C.,Caillaux, B.,Viehe, H. G.
, p. 3331 - 3338 (2007/10/02)
Chlorination of saturated amide chlorides followed by hydrolysis, thiolysis, aminolysis and catalysed dehydrochlorination leads to α-chloro acrylamide derivatives in high yield.The reaction sequence is applied to lactames and can also be extended to the synthesis of α-chloro acrylthioamide and amidine.