86838-43-9Relevant articles and documents
Enantioselective synthesis of α-benzyloxy-ω-alkenals: application to the synthesis of (+)-exo-brevicomin, (+)-iso-exo-brevicomin, and (-)-isolaurepan
Prasad, Kavirayani R.,Anbarasan, Pazhamalai
, p. 1419 - 1427 (2008/02/11)
The enantioselective synthesis of α-benzyloxy aldehydes containing a terminal alkene was carried out from chiral pool l-(+)-tartaric acid by employing the stereoselective reduction of a 1,4-diketone as the key step. The synthetic utility of these aldehyde
Synthesis of (+)-endo- and (+)-exo-brevicomin viaenzyme-mediated hydrolysis of an enol ester
Matsumoto, Kazutsugu,Suzuki, Natsuko,Ohta, Hiromiehi
, p. 7163 - 7166 (2007/10/02)
Optically pure (+)-endo- and (+)-exo-brevicomin have been synthesized in short steps starting from α-hydroxy ketone derivative, (R)-4-benzyloxy-8-nonen-3-one (3), which was prepared via enzymatic hydrolysis of racemic enol ester 4.