86855-26-7

Basic information

• Product Name: hexadecanesulfonyl fluoride
• Synonyms: hexadecanesulfonyl fluoride;QIVFMUVBIHIZAM-UHFFFAOYSA-N
• CAS NO: 86855-26-7
• Molecular Formula: C₁₆H₃₃FO₂S
• Molecular Weight: 308.5
• Mol File: 86855-26-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 388.3°C at 760 mmHg
• Flash Point: 188.6°C
• Appearance: /
• Density: 0.966g/cm³
• Vapor Pressure: 6.93E-06mmHg at 25°C
• Refractive Index: 1.445
• CAS DataBase Reference: hexadecanesulfonyl fluoride(CAS DataBase Reference)
• NIST Chemistry Reference: hexadecanesulfonyl fluoride(86855-26-7)
• EPA Substance Registry System: hexadecanesulfonyl fluoride(86855-26-7)

Safety Data

• Hazardous Substances Data: 86855-26-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H33FO2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(17,18)19/h2-16H2,1H3

Upstream product

• 19218-94-1 1-iodotetradecane 
• 677-25-8 ethylenesulfonyl fluoride 
• 38775-38-1 1-hexadecanesulfonyl chloride 

Downstream Products

• 86855-25-6 2-(Hexadecane-1-sulfonyl)-1,4-dimethyl-benzene 

Relevant articles and documents

Catalytic Decarboxylative Fluorosulfonylation Enabled by Energy-Transfer-Mediated Photocatalysis

Sulfonyl fluorides are useful building blocks in a wide array of fields. Herein, we report a catalytic decarboxylative fluorosulfonylation approach for converting abundant aliphatic carboxylic acids to the corresponding sulfonyl fluorides. This transformation is enabled by simple preactivation as aldoxime esters and energy-transfer-mediated photocatalysis. This operationally simple method proceeds with high functional-group tolerance under mild and redox-neutral conditions.

Inhibition of lipoprotein lipase by alkanesulfonyl fluorides

A number of alkanesulfonyl halides (chlorides and fluorides) and esters were synthesized and their effect on the activity of lipoprotein lipase (LPL) was studied. Sulfonyl fluorides proved to be efficient inhibitors of LPL when the enzyme was incubated with a 10-fold molar excess of the inhibitors in a buffer containing bile salts (deoxycholate). Hexadecane- and dodecanesulfonyl fluorides caused 50% inhibition of LPL activity at concentrations of 10 to 20 μM. (C) 2000 Elsevier Science Ltd.