868696-17-7

Basic information

• Product Name: 1,2,5-Trioxaspiro[5.5]undecan-9-ol, 3-(1-phenylethenyl)-
• CAS NO: 868696-17-7
• Molecular Formula: C16H20O4
• Molecular Weight: 276.332
• Mol File: 868696-17-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2,5-Trioxaspiro[5.5]undecan-9-ol, 3-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Trioxaspiro[5.5]undecan-9-ol, 3-(1-phenylethenyl)-(868696-17-7)
• EPA Substance Registry System: 1,2,5-Trioxaspiro[5.5]undecan-9-ol, 3-(1-phenylethenyl)-(868696-17-7)

Safety Data

• Hazardous Substances Data: 868696-17-7(Hazardous Substances Data)

Upstream product

• 132533-03-0 3-phenyl-2-hydroperoxybut-3-en-1-ol 
• 678967-25-4 3-(1-Phenyl-vinyl)-1,2,5-trioxaspiro[5.5]undec-9-one 
• 54976-38-4 (E)-3-phenylbut-2-en-1-ol 

Downstream Products

• 872891-56-0 succinic acid methyl ester 3-(1-phenylvinyl)-1,2,5-trioxaspiro[5.5]undec-9-yl ester 
• 13482-22-9 4-hydroxycyclohexanone 

Relevant articles and documents

Orally active 1,2,4-trioxanes: Synthesis and antimalarial assessment of a new series of 9-functionalized 3-(1-arylvinyl)-1,2,5-trioxaspiro[5.5]undecanes against multi-drug-resistant Plasmodium yoelii nigeriensis in mice

Using easily accessible keto-trioxanes 7a-g as the starting materials, a series of new variously functionalized 1,2,4-trioxanes 10-36 have been prepared and evaluated for antimalarial activity against multi-drug-resistant Plasmodium yoelii nigeriensis in

Protection of the carbonyl group as 1,2,4-trioxane and its regeneration under basic conditions

(Chemical Equation Presented) An experimental protocol demonstrating the protection of the carbonyl group as 1,2,4-trioxane, the stability of the protecting group under a variety of reaction conditions, and the regeneration of the carbonyl group with Triton B in THF at room temperature is presented. The method provides a useful alternative for the protection of carbonyl compounds having acid-sensitive moieties.