86882-17-9

Basic information

• Product Name: 4-Chloro-2-(2-thiophen-2-yl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-phenol
• CAS NO: 86882-17-9
• Molecular Weight: 371.911
• Mol File: 86882-17-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Chloro-2-(2-thiophen-2-yl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-(2-thiophen-2-yl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-phenol(86882-17-9)
• EPA Substance Registry System: 4-Chloro-2-(2-thiophen-2-yl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-phenol(86882-17-9)

Safety Data

• Hazardous Substances Data: 86882-17-9(Hazardous Substances Data)

Upstream product

• 7209-80-5 1-(5-chloro-2-hydroxy-phenyl)-3-thiophen-2-yl-propenone 
• 137-07-5 2-amino-benzenethiol 

Downstream Products

• 86882-48-6 4-Chloro-2-(1,1-dioxo-2-thiophen-2-yl-2,3-dihydro-1H-1λ⁶-benzo[b][1,4]thiazepin-4-yl)-phenol 

Relevant articles and documents

Synthesis of 2,4-Diaryl-2,3-dihydro-1,5-benzothiazepines & their 1,1-Dioxides as antibacterial Agents

o-Aminothiophenol reacts with chalkones (I) in methanol-acetic acid to give 3-(2-aminophenylmercapto)-3-arylpropiophenones (II) which immediately undergo cyclization in situ to give 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines (IIIa).Compounds IIIa are easily oxidised to the corresponding 1,1-dioxides (IV) by H2O2 (30percent) in gl. acetic acid.A few compunds have been screened for their antibacterial activity against S. aureus, S. typhi., V.Comma and E. coli.