86926-16-1 Usage
Description
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE is a chiral amine compound with a non-superimposable mirror image, where the (R)-enantiomer is the active form. It is widely utilized in the field of organic synthesis, particularly for the production of pharmaceuticals and fine chemicals. Additionally, it serves as a catalyst in various chemical reactions, such as asymmetric synthesis, and plays a crucial role in the development of new drugs and materials. Its unique structure and properties make it a valuable asset in medicinal and organic chemistry.
Uses
Used in Pharmaceutical Industry:
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE is used as a reagent for the synthesis of various pharmaceuticals and fine chemicals. Its unique properties and chiral nature enable the creation of specific drug molecules with desired therapeutic effects.
Used in Organic Synthesis:
In the field of organic chemistry, (R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE is used as a catalyst in asymmetric synthesis. Its ability to selectively promote certain reactions contributes to the development of enantiomerically pure compounds, which are essential for the production of effective and safe drugs.
Used in Catalyst Development:
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE is employed in the development of new catalysts for various chemical reactions. Its unique structure allows for the design of catalysts that can improve reaction efficiency, selectivity, and overall yield, leading to more sustainable and cost-effective chemical processes.
Used in Research and Development:
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE is also used in research and development for the discovery and optimization of new drugs and materials. Its application in medicinal chemistry helps scientists understand the structure-activity relationships of potential drug candidates and develop more effective therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 86926-16-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,9,2 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 86926-16:
(7*8)+(6*6)+(5*9)+(4*2)+(3*6)+(2*1)+(1*6)=171
171 % 10 = 1
So 86926-16-1 is a valid CAS Registry Number.
86926-16-1Relevant articles and documents
Cu2O-catalyzed C–S coupling of quaternary ammonium salts and sodium alkane-/arene-sulfinates
Chen, Hongyi,Huang, Youming,Zeng, Qingle,Zheng, Wenting
supporting information, (2020/08/28)
A new protocol for the synthesis of (enantioenriched) benzylic sulfones via the Cu2O-catalyzed C–S bond cross coupling of alkane-/arene-sulfinates and (enantioenriched) benzylic quaternary ammonium salts has been developed. The product benzylic sulfones were obtained in good to high yields (75–96%). Chiral arylmethyl sulfones with high enantiomeric excess (90–94% ee) were also synthesized in the presence of Cu2O and 1,1′-bis-(diphenylphosphino)ferrocene (dppf).
Metallation of benzylic amines via amine-borane complexes
Ebden, Mark R.,Simpkins, Nigel S.,Fox, David N.A.
, p. 12923 - 12952 (2007/10/03)
Formation of borane complexes of N,N-dimethylbenzylamine, N,N- dimethyl(1-naphthyl)methylamine, N,N-dimethyl(2-naphthyl)methylamine, N- methyltetrahydroisoquinoline and N-methylisoindoline facilitates regioselective metallation of these systems using BuLi, giving intermediate benzylic anions which react with a range of electrophiles to give products in good yield.
