869681-70-9

Basic information

• Product Name: 4-Boc-3(R)-morpholinecarboxylic acid
• Synonyms: (R)-N-Boc-morpholine-3-carboxylic acid;4-Boc-3(R)-morpholinecarboxylic acid;(R)-Morpholine-3,4-dicarboxylic acid 4-tert-butyl ester;3,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) ester, (3R)-;(R)-4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid;(3R)-4-[(tert-butoxy)carbonyl]Morpholine-3-carboxylic acid;(R)-N-tert-butoxycarbonylMorpholine-3-carboxylicacid;(R)-4-N-Boc-3-Morpholinecarboxylic acid
• CAS NO: 869681-70-9
• Molecular Formula: C₁₀H₁₇NO₅
• Molecular Weight: 231.25
• Product Categories: Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Morpholines/Thiomorpholines;New Products for Chemical Synthesis;C4 to C10
• Mol File: 869681-70-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 181℃
• Boiling Point: 369.5 °C at 760 mmHg
• Flash Point: 177.3 °C
• Appearance: White/Powder
• Density: 1.23 g/cm³
• Vapor Pressure: 1.8E-06mmHg at 25°C
• Refractive Index: 1.492
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.53±0.20(Predicted)
• CAS DataBase Reference: 4-Boc-3(R)-morpholinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Boc-3(R)-morpholinecarboxylic acid(869681-70-9)
• EPA Substance Registry System: 4-Boc-3(R)-morpholinecarboxylic acid(869681-70-9)

Safety Data

• RIDADR: UN2811
• HazardClass: 6.1
• Hazardous Substances Data: 869681-70-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H17NO5/c1-10(2,3)16-9(14)11-4-5-15-6-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1

Upstream product

• 714971-28-5 (S)-3-(hydroxymethyl)morpholine-4-carboxylic acid tert-butyl ester 
• 211053-50-8 (S)-3-(hydroxymethyl)morpholine 
• 1235387-14-0 C₁₃H₁₇NO₃ 
• 885321-46-0 (R)-methyl N-tert-butoxycarbonylmorpholine-3-carboxylate 
• 1373883-17-0 (S)-2-chloroacetylamino-3-hydroxypropionic acid ethyl ester 
• 1207428-21-4 C₈H₁₁N*C₁₀H₁₇NO₅ 
• 885321-34-6 (R)-3-(tert-butyldiphenylsilyloxymethyl)morpholine 

Downstream Products

• 714971-28-5 (S)-3-(hydroxymethyl)morpholine-4-carboxylic acid tert-butyl ester 
• 1229649-22-2 (R)-N-(4-((4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ureido)naphthalen-1-yloxy)methyl)pyridin-2-yl)morpholine-3-carboxamide 
• 1189569-40-1 (2R)-5-{(1E)-3-[(7R,9aR)-7-(3,5-difluorophenyl)-9-oxohexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]prop-1-en-1-yl}-1,3-dihydrospiro[indene-2,3 '-pyrrolo[2,3-b]pyridin]-2'(1'H)-one 5 
• 1189570-08-8 (9aR)-8-allyl-7(R)-(3,5-difluorophenyl)hexahydropyrazino[2,1-c][1,4]oxazin-9(6H)-one 
• 1189570-10-2 (9aR)-8-allyl-7(S)-(3,5-difluorophenyl)hexahydropyrazino[2,1-c][1,4]oxazin-9(6H)-one 
• 1189570-09-9 methyl 4-[2-(3,5-difluorophenyl)-2-oxoethyl]morpholine-3(R)-carboxylate 
• 1190115-55-9 (R)-(4-(4-(4-(2-(isopropylsulfonyl)phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)-5-methoxy-2-methylphenyl)piperidin-1-yl)(morpholin-3-yl)methanone 
• 911223-07-9 (R)-3-{4-chloro-2-[3-(5-methyl-pyrazin-2-yl)-ureido]-phenoxymethyl}-morpholine-4-carboxylic acid tert-butyl ester 
• 911223-05-7 (R)-3-(4-chloro-2-nitro-phenoxymethyl)-morpholine-4-carboxylic acid tert-butyl ester 
• 911223-06-8 (R)-3-(2-amino-4-chloro-phenoxymethyl)-morpholine-4-carboxylic acid tert-butyl ester 
• 1257850-86-4 (R)-3-formylmorpholin-4-carboxylic acid tert-butyl ester 

Relevant articles and documents

Preparation method of chiral N-tert-butyloxycarborylmorpholine-3-carboxylic acid

The invention provides a preparation method of chiral N-tert-butyloxycarborylmorpholine-3-carboxylic acid, which comprises the following steps: (1) carrying out an amino protection reaction on chiralserinamide and an amino protective agent to obtain a com

CRYSTALLINE FORMS OF A PYRIDINE DERIVATIVE

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