869718-81-0 Usage
Description
3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine, also known as m-PEG8-amine, is a polyethylene glycol (PEG)-based compound with an amine functional group at one end and multiple ether linkages along its backbone. The hydrophilic PEG spacer increases its solubility in aqueous media, making it a versatile building block for various applications.
Uses
Used in Bioconjugation:
3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine is used as a bioconjugation agent for attaching biologically active molecules, such as peptides, proteins, or drugs, to other molecules or surfaces. Its reactivity with carboxylic acids, activated NHS esters, and carbonyls allows for stable and specific conjugation.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The hydrophilic PEG spacer can reduce the immunogenicity and non-specific interactions of the drug, leading to enhanced circulation time and targeted delivery.
Used in Diagnostic Imaging:
3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine is used as a contrast agent or a component in the development of imaging probes for various diagnostic modalities, such as magnetic resonance imaging (MRI), computed tomography (CT), or positron emission tomography (PET). The PEG spacer can improve the stability and biocompatibility of the imaging agents, allowing for better imaging resolution and reduced side effects.
Used in Hydrogels and Tissue Engineering:
In the field of tissue engineering, 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine is used as a component in the design and fabrication of hydrogels for tissue regeneration and repair. The hydrophilic PEG spacer can provide a favorable microenvironment for cell adhesion, proliferation, and differentiation, promoting tissue integration and healing.
Used in Surface Modification:
3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine is used for surface modification of various materials, such as nanoparticles, implants, or sensors, to enhance their biocompatibility, stability, or functionality. The PEG spacer can provide a protective layer, reducing non-specific interactions and improving the overall performance of the modified surfaces.
Check Digit Verification of cas no
The CAS Registry Mumber 869718-81-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,7,1 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 869718-81:
(8*8)+(7*6)+(6*9)+(5*7)+(4*1)+(3*8)+(2*8)+(1*1)=240
240 % 10 = 0
So 869718-81-0 is a valid CAS Registry Number.
869718-81-0Relevant articles and documents
A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS
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Page/Page column 226-227, (2021/01/23)
Provided is a conjugation of cytotoxic drug to a cell-binding molecule with a side-chain linker. It provides side-chain linkage methods of making a conjugate of a cytotoxic molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and immunological disorders.
Antioxidants Having Aromatic Structures Reacting with Superoxide
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Sheet 4, (2016/07/27)
Disclosed is a method of treating diseases which are: reactive oxygen species mediated, ischemic or reperfusion-related, or T-cell mediated, including autoimmune diseases. The method is administering a therapeutically effective amount of a formulation wherein the active ingredient includes non-phenolic aromatic structures that are electron deficient and are capable of converting the superoxide radical to O2; and/or of converting superoxide radical to oxygen and hydrogen peroxide, or pharmaceutically acceptable salts of said structures. Also disclosed is a method of diagnosing and treating such diseases and conditions.
