869789-69-5Relevant articles and documents
Direct Access to Highly Enantioenriched α-Branched Acrylonitriles through a One-Pot Sequential Asymmetric Michael Addition/Retro-Dieckmann/Retro-Michael Fragmentation Cascade
Duchemin, Nicolas,Cattoen, Martin,Gayraud, Oscar,Anselmi, Silvia,Siddiq, Bilal,Buccafusca, Roberto,Daumas, Marc,Ferey, Vincent,Smietana, Michael,Arseniyadis, Stellios
supporting information, p. 5995 - 6000 (2020/08/28)
A highly enantioselective synthesis of α-branched acrylonitriles is reported featuring a one-pot sequential asymmetric Michael addition/retro-Dieckmann/retro-Michael fragmentation cascade. The method, which relies on a solid, bench-stable, and commercially available acrylonitrile surrogate, is practical, scalable, and highly versatile and provides a direct access to a wide range of enantioenriched nitrile-containing building blocks. Most importantly, the method offers a new tool to incorporate an acrylonitrile moiety in an asymmetric fashion.
Expanding biohybrid-mediated asymmetric catalysis into the realm of RNA
Duchemin, Nicolas,Benedetti, Erica,Bethge, Lucas,Vonhoff, Stefan,Klussmann, Sven,Vasseur, Jean-Jacques,Cossy, Janine,Smietana, Michael,Arseniyadis, Stellios
supporting information, p. 8604 - 8607 (2016/07/14)
The recent development of biohybrid catalytic systems has allowed synthetic chemists to reach high levels of selectivity on a wide variety of valuable synthetic transformations. In this context, DNA-based catalysts have emerged as particularly appealing t
DNA vs. mirror-image DNA: A universal approach to tune the absolute configuration in DNA-based asymmetric catalysis
Wang, Jocelyn,Benedetti, Erica,Bethge, Lucas,Vonhoff, Stefan,Klussmann, Sven,Vasseur, Jean-Jacques,Cossy, Janine,Smietana, Michael,Arseniyadis, Stellios
supporting information, p. 11546 - 11549 (2013/11/06)
Mirror mirror on the wall: By taking advantage of the unique structural features of L-DNA, the first examples of left-helical enantioselective induction in the field of DNA-based asymmetric catalysis were realized. Most importantly, this approach is the o