870114-99-1

Basic information

• Product Name: 2-(3,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester
• Synonyms: 2-(3,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester
• CAS NO: 870114-99-1
• Molecular Weight: 335.189
• Mol File: 870114-99-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester(870114-99-1)
• EPA Substance Registry System: 2-(3,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester(870114-99-1)

Safety Data

• Hazardous Substances Data: 870114-99-1(Hazardous Substances Data)

Upstream product

• 6287-38-3 3,4-dichlorobenzaldehyde 
• 37466-90-3 ethyl 3,4-diaminobenzoate 

Downstream Products

• 1393711-29-9 2-(3,4-dichlorophenyl)-N-[2-(1,4,5,6-tetrahydropyrimidin-2-yl)ethyl]-1H-benzimidazole-5-carbox-amide 
• 1393711-28-8 2-(3,4-dichlorophenyl)-N-{3-imino-3-[(1-methylethyl)amino]propyl}-1H-benzimidazole-5-carboxamide 
• 1393711-27-7 N-(3-amino-3-iminopropyl)-2-(3,4-dichlorophenyl)-1H-benzimidazole-5-carboxamide 
• 1393711-24-4 N-(2-cyanoethyl)-2-(3,4-dichlorophenyl)-1H-benzimidazole-5-carboxamide 
• 870115-25-6 2-(3,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid 

Relevant articles and documents

Synthesis and potent antibacterial activity against MRSA of some novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5-carboxamidines

A series of 28 novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5- carboxamidine derivatives were synthesized and evaluated for in vitro antibacterial activities against Staphylococcus aureus and methicillin resistant S. aureus (MRSA) by the tube dilution method. The results showed that compounds 45-46 and 55-57, having 3,4-dichloro substituted phenyl at the position C-2, of N-bulky alkyl substituted benzimidazolecarboxamidines exhibited the greatest activity with MIC values of 1.56-0.39 μg/ml.