87014-30-0

Basic information

• Product Name: Benzene, 1-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)-
• CAS NO: 87014-30-0
• Molecular Formula: C9H6F6O
• Molecular Weight: 244.136
• Mol File: 87014-30-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)-(87014-30-0)
• EPA Substance Registry System: Benzene, 1-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)-(87014-30-0)

Safety Data

• Hazardous Substances Data: 87014-30-0(Hazardous Substances Data)

Upstream product

• 75-89-8 2,2,2-trifluoroethanol 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 98-56-6 4-chlorobenzotrifluoride 
• 402-45-9 4-hydroxybenzotrifluoride 
• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 420-87-1 sodium 2,2,2-trifluoroethanolate 

Relevant articles and documents

A Unified and Practical Method for Carbon–Heteroatom Cross-Coupling using Nickel/Photo Dual Catalysis

While carbon–heteroatom cross-coupling reactions have been extensively studied, many methods are specific and limited to a particular set of substrates or functional groups. Reported here is a general method that allows for C?O, C?N and C?S cross-coupling reactions under one general set of conditions. We propose that an energy transfer pathway, in which an iridium photosensitizer produces an excited nickel(II) complex, is responsible for the key reductive elimination step that couples aryl bromides, iodides, and chlorides to 1° and 2° alcohols, amines, thiols, carbamates, and sulfonamides, and is amenable to scale up via a flow apparatus.

Facile and efficient synthesis of fluoroalkyl aryl ethers

A convenient and practical method for the preparation of fluoroalkyl aryl ethers via substitution of iodoalkyl fluorides is described. This method involves KF complexation of the phenol, which increases the nucleophilicity of oxygen for the formation of the ether linkage.