87100-28-5Relevant articles and documents
Selective Benzylic CH-Borylations by Tandem Cobalt Catalysis
Bauer, Matthias,Ghosh, Pradip,Jacobi von Wangelin, Axel,Schoch, Roland
, (2021/11/27)
Metal-catalyzed C?H activations are environmentally and economically attractive synthetic strategies for the construction of functional molecules as they obviate the need for pre-functionalized substrates and minimize waste generation. Great challenges reside in the control of selectivities, the utilization of unbiased hydrocarbons, and the operation of atom-economical dehydrocoupling mechanisms. An especially mild borylation of benzylic CH bonds was developed with the ligand-free pre-catalyst Co[N(SiMe3)2]2 and the bench-stable and inexpensive borylation reagent B2pin2 that produces H2 as the only by-product. A full set of kinetic, spectroscopic, and preparative mechanistic studies are indicative of a tandem catalysis mechanism of CH-borylation and dehydrocoupling via molecular CoI catalysts.
The functionalization of benzene by boranes using trispyrazolylborate complexes
Vetter, Andrew J.,DiBenedetto, Tarah A.,Ritz, Mikhaila D.,Jones, William D.
, (2021/02/03)
The catalytic C[sbnd]H activation and borylation of arenes by trispyrazolylborate complexes is reported. Trispyrazolylborate rhodium and iridium complexes have been previously shown to activate a variety of C[sbnd]H bonds. Here, we show the catalytic borylation of arenes by the trispyrazolylborate ethylene complexes Tp'Rh(C2H4)2, and Tp'Ir(C2H4)2.
Boronic acid derivatives
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Paragraph 0113; 0124-0127; 0302; 0305-0308, (2021/07/21)
The present invention relates to boronic acid derivatives; the present invention provides compounds of formula (I) or pharmaceutically acceptable salts, solvates, polymorphs or isomers thereof, pharmaceutical compositions comprising these compounds, and uses of such compounds in the treatment of lmp7-related diseases.
