871013-92-2

Basic information

• Product Name: tert-butyl 4-hydroxyisoindoline-2-carboxylate
• Synonyms: tert-butyl 4-hydroxyisoindoline-2-carboxylate;tert-butyl 4-hydroxy-2,3-dihydro-1H-isoindole-2-carboxylate
• CAS NO: 871013-92-2
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.27898
• Mol File: 871013-92-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 359.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.205±0.06 g/cm3(Predicted)
• PKA: 9.77±0.20(Predicted)
• CAS DataBase Reference: tert-butyl 4-hydroxyisoindoline-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-hydroxyisoindoline-2-carboxylate(871013-92-2)
• EPA Substance Registry System: tert-butyl 4-hydroxyisoindoline-2-carboxylate(871013-92-2)

Safety Data

• Hazardous Substances Data: 871013-92-2(Hazardous Substances Data)

Usage

Description

Tert-butyl 4-hydroxyisoindoline-2-carboxylate is a chemical compound with the molecular formula C14H17NO4. It is an ester derivative of 4-hydroxyisoindoline-2-carboxylic acid, featuring a tert-butyl group attached to the nitrogen atom and a carboxylic acid group. tert-butyl 4-hydroxyisoindoline-2-carboxylate is known for its potential antioxidant and antitumor activities, as well as its unique structure and reactivity, which make it a valuable intermediate in the synthesis of various pharmaceuticals, agricultural chemicals, and specialty chemicals.

Uses

Used in Pharmaceutical Industry:
Tert-butyl 4-hydroxyisoindoline-2-carboxylate is used as a building block for the preparation of various pharmaceuticals due to its potential antioxidant and antitumor activities. Its unique structure and reactivity allow for the development of new drugs with improved therapeutic properties.
Used in Agricultural Chemical Industry:
In the agricultural chemical industry, tert-butyl 4-hydroxyisoindoline-2-carboxylate is utilized as a key intermediate in the synthesis of various agrochemicals, contributing to the development of effective and environmentally friendly products for crop protection and enhancement.
Used in Specialty Chemicals Production:
Tert-butyl 4-hydroxyisoindoline-2-carboxylate is employed as a valuable intermediate in the production of specialty chemicals, where its unique structure and reactivity play a crucial role in creating innovative and high-performance products for various applications.

Upstream product

• 491875-13-9 4-hydroxy-2-(4-methoxybenzyl)-1H-isoindole-1,3(2H)-dione 
• 37418-88-5 3-hydroxyphthalic anhydride 
• 135414-50-5 1,3-dioxo-3,3a,7,7a-tetrahydro-4,7-epoxy-2-benzofuran-4(1H)-yl 2,2-dimethyl-propanoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1035235-27-8 tert-butyl 4-bromo-2,3-dihydro-1H-isoindole-2-carboxylate 
• 1035235-28-9 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-2-carboxylic acid tert-butyl ester 

Downstream Products

• 127168-73-4 4-methoxy-1H-isoindole 

Relevant articles and documents

INHIBITORS OF MLH1 AND/OR PMS2 FOR CANCER TREATMENT

The present invention relates to compounds of Formula (I) that target the MLH1 and/or PMS2 proteins that are components of the DNA Mismatch Repair (MMR) process: Formula (I) wherein R1, R2, R3, R4, R6

RHO KINASE INHIBITORS

The invention provides novel inhibitors of ROCK1 and/or ROCK2. Also provided are methods of treating diseases and disorders involving inhibiting ROCK1 and/or ROCK2. The present invention includes pharmaceutical compositions comprising the compounds of the invention and a pharmaceutically acceptable carrier and/or diluents. The present invention includes compositions comprising a substantially pure compound of the invention and a pharmaceutically acceptable salt, steroisomer, or hydrate thereof: and a pharmaceutically acceptable excipient and/or diluents.