871826-47-0 Usage
General Description
10(S),17(S)-DiHDoHE, also known as 10(S),17(S)-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid, is a bioactive lipid derived from the omega-3 polyunsaturated fatty acid, docosahexaenoic acid (DHA). It is a specialized pro-resolving mediator (SPM) that plays a crucial role in the resolution of inflammation and tissue repair. 10(S),17(S)-DiHDoHE has been found to have potent anti-inflammatory and pro-resolving properties, and it has been implicated in the regulation of various biological processes such as immune response, tissue regeneration, and pain modulation. It is also believed to have beneficial effects on cardiovascular health and neurological function. Overall, 10(S),17(S)-DiHDoHE represents a promising target for the development of novel therapeutics for inflammation-related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 871826-47-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,8,2 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 871826-47:
(8*8)+(7*7)+(6*1)+(5*8)+(4*2)+(3*6)+(2*4)+(1*7)=200
200 % 10 = 0
So 871826-47-0 is a valid CAS Registry Number.
871826-47-0Relevant articles and documents
TOTAL SYNTHESES OF SPECIALIZED PRO-RESOLVING MEDIATORS (SPMS), STRUCTURAL ISOMERS AND STRUCTURAL ANALOGS
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, (2022/02/09)
A method for the synthesis of specialized pro-resolving mediators, structural isomers thereof and analogs thereof is disclosed herein. The method comprises reacting a compound of the formula (I): (I) wherein R1 is alkyl(C≤12), cycloalkyl(C≤12), alkenyl(C≤12), alkylidene(C≤12), alkynyl(C≤12), aryl, aralkyl, heteroaryl or heteroaralkyl; and X1, X2 and X3 are each independently hydroxy or OP, wherein P is a hydroxy protecting or hydroxy activating group; with a reducing agent under conditions sufficient to produce a compound of the formula (II): (II) wherein: R1, X1, X2 and X3 are as defined above. Novel protectins, more specifically novel structural isomers and analogs of PD1 and PDX are also disclosed.
