872001-34-8

Basic information

• Product Name: C₂₇H₃₇N₃O₂
• Synonyms: C₂₇H₃₇N₃O₂
• CAS NO: 872001-34-8
• Molecular Weight: 435.61
• Mol File: 872001-34-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₇N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₇N₃O₂(872001-34-8)
• EPA Substance Registry System: C₂₇H₃₇N₃O₂(872001-34-8)

Safety Data

• Hazardous Substances Data: 872001-34-8(Hazardous Substances Data)

Upstream product

• 172739-04-7 cis-3-benzyl-3,7-diazabicyclo[3.3.0]octane 
• 135865-78-0 tert-butyl (1S)-3-oxo-1-phenylpropylcarbamate 

Downstream Products

• 872001-43-9 C₂₂H₂₉N₃*ClH 
• 872001-35-9 C₂₀H₃₁N₃O₂ 

Relevant articles and documents

Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists

Starting with a high-throughput screening lead, a novel series of CCR5 antagonists was developed utilizing an information-based approach. Improvement of pharmacokinetic properties for the series was pursued by SAR exploration of the lead template. The synthesis, SAR and biological profiles of the series are described.

Heterocyclic antiviral compounds

Chemokine receptor antagonists, in particular, 3,7-diazabicyclo[3.3.0]octane compounds according to formula (I) wherein R1-R3 R6c and X1 are as defined herein are antagonists of chemokine CCR5 receptors which ar