872036-78-7Relevant articles and documents
Esters and amides of 2,3-dimethoxy-8,9-methylenedioxy-benzo[i] phenanthridine-12-carboxylic acid: Potent cytotoxic and topoisomerase I-targeting agents
Zhu, Shejin,Ruchelman, Alexander L.,Zhou, Nai,Liu, Angela A.,Liu, Leroy F.,LaVoie, Edmond J.
, p. 6782 - 6794 (2007/10/03)
The exceptional topoisomerase I-targeting activity and antitumor activity of 5-(2-N,N-dimethylamino)ethyl-8,9-dimethoxy-2,3-methylenedioxy-5H-dibenzo[c,h] [1,6]naphthyridin-6-one (ARC-111, topovale) prompted studies on similarly substituted benzo[i]phenan