87216-87-3

Basic information

• Product Name: t-BuOCO-L-Pro-Gly-L-Tyr(CH₂Ph)-OCH₂Ph
• CAS NO: 87216-87-3
• Molecular Weight: 615.726
• Mol File: 87216-87-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: t-BuOCO-L-Pro-Gly-L-Tyr(CH₂Ph)-OCH₂Ph(CAS DataBase Reference)
• NIST Chemistry Reference: t-BuOCO-L-Pro-Gly-L-Tyr(CH₂Ph)-OCH₂Ph(87216-87-3)
• EPA Substance Registry System: t-BuOCO-L-Pro-Gly-L-Tyr(CH₂Ph)-OCH₂Ph(87216-87-3)

Safety Data

• Hazardous Substances Data: 87216-87-3(Hazardous Substances Data)

Upstream product

• 76912-67-9 t-BuOCO-Gly-L-Tyr(CH₂Ph)-OCH₂Ph 
• 52142-01-5 H-Tyr(Bzl)-OBzl_.HCl 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 87216-86-2 Gly-L-Tyr(CH₂Ph)-OCH₂Ph hydrochloride 

Downstream Products

• 87216-88-4 L-Pro-Gly-L-Tyr(CH₂Ph)-OCH₂Ph hydrochloride 

Relevant articles and documents

Specific Binding of the Tyrosine Residue in Copper(II) Complexes of Tyr-Pro-Gly-Tyr and Tyr-Gly-Pro-Tyr

The syntheses of the tetrapeptides Tyr-Pro-Gly-Tyr and Tyr-Gly-Pro-Tyr (H3L) are reported, together with the results of a potentiometric and spectrophotometric study of their H+ and Cu2+ complexes.Proline acts as a break-point to metal-ion co-ordination when inserted into a peptide chain and in Tyr(1)-Pro(2)-Gly(3)-Tyr(4) the Pro residue enforces a bent conformation and the formation of an unusually stable complex with co-ordination through the terminal amine-N of Tyr(1), the neighbouring peptide=CO, and the OTyr- of Tyr(4).This necessitates a 17-membered chelate ring.With Tyr-Gly-Pro-Tyr there is also OTyr--C bonding but this is a result of dimer formation in 2-.