87240-01-5

Basic information

• Product Name: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole-6(5H)-thione, 3-(4-chlorophenyl)-
• CAS NO: 87240-01-5
• Molecular Formula: C9H5ClN4S2
• Molecular Weight: 268.75
• Mol File: 87240-01-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole-6(5H)-thione, 3-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole-6(5H)-thione, 3-(4-chlorophenyl)-(87240-01-5)
• EPA Substance Registry System: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole-6(5H)-thione, 3-(4-chlorophenyl)-(87240-01-5)

Safety Data

• Hazardous Substances Data: 87240-01-5(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 68468-95-1 4-amino-5-(4-chlorophenyl)-2,4-dihydro-3H[1,2,4]triazole-3-thione 

Relevant articles and documents

Synthesis of Heterocycles. Part VII . Synthesis and Antimicrobial Activity of Some 7H-s-Triazolothiadiazine and s-Triazolothiadiazole Derivatives

The cyclization of 4-amino-5-aryl-3-cyanomethylthio-1,2,4-triazoles II in the presence of concentrated sulfuric acid yields 7H-6-amino-s-triazolothiadiazines III.Cyclization of 4-amino-5-aryl-1,2,4-triazole-3-thiones I with phenacyl chloride yields 7H-3-aryl-6-phenyl-s-triazolothiadiazines IV.Similarly, compounds I condensed with cyanogen bromide, phenyl isothiocyanate and carbon disulfide to give the corresponding cyclized products 6-amino-3-aryl-s-triazolothiadiazoles V, 3-aryl-6-phenylamino-s-triazolothiadiazoles VI and 3-aryl-s-triazolothiadiazol-6(5H)thiones VII, respectively.Also in the presence of phosphoryl chloride, compounds I underwent cyclization with monocarboxylic acids and oxalic acid to 3,6-diaryl-s-triazolothiadiazole VIII and 6,6'-bis(3-aryl-s-triazolothiadiazoles) IX.The above compounds were screened for their antimicrobial activity.