872611-16-0 Usage
Description
O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl Carbamate is a white crystalline solid that functions as an inhibitor of both N-acetylglucosaminidase and O-GlcNAcase enzymes.
Uses
Used in Pharmaceutical Industry:
O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl Carbamate is used as an enzyme inhibitor for the treatment of various diseases and conditions. Its ability to inhibit N-acetylglucosaminidase and O-GlcNAcase enzymes makes it a potential candidate for therapeutic applications in the pharmaceutical industry.
Used in Research Applications:
O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl Carbamate is used as a research tool to study the role and function of N-acetylglucosaminidase and O-GlcNAcase enzymes in various biological processes. This can help researchers gain a better understanding of the underlying mechanisms of certain diseases and develop targeted therapies.
Used in Drug Development:
O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl Carbamate is used in the development of new drugs targeting N-acetylglucosaminidase and O-GlcNAcase enzymes. Its inhibitory properties can be leveraged to create novel therapeutic agents for the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 872611-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,2,6,1 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 872611-16:
(8*8)+(7*7)+(6*2)+(5*6)+(4*1)+(3*1)+(2*1)+(1*6)=170
170 % 10 = 0
So 872611-16-0 is a valid CAS Registry Number.
872611-16-0Relevant articles and documents
An improved route to PUGNAc and its Galacto -configured congener
Goddard-Borger, Ethan D.,Stubbs, Keith A.
scheme or table, p. 3931 - 3934 (2010/08/06)
Figure presented An efficient, scalable, and reliable synthesis of PUGNAc and its galacto-configured congener is reported.
SELECTIVE GLYCOSIDASE INHIBITORS, METHODS OF MAKING INHIBITORS, AND USES THEREOF
-
Page/Page column 47; 52-53, (2010/11/23)
The invention comprises compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions containing the compounds or prodrugs of the compounds. The invention also comprises animal models and methods of making the animal models for studying diseases and disorders related to deficiency or overexpression of O-GIcNAcase, accumulation or deficiency of O-GIcNAc, and treatment of such diseases and disorders. The invention also comprises methods of treating such diseases and disorders. The invention also comprises methods of making the compounds, and methods of making selective glycosidase inhibitors
An improved synthesis of 2-acetamido-2-deoxy-D-gluconohydroximolactone (PUGNAc), a strong inhibitor of β-N-acetylglucosaminidases
Mohan, Halasyam,Vasella, Andrea
, p. 114 - 118 (2007/10/03)
O-(2-Acetamido-3,4,6-tri-O-acetyl-D-glucopyranosylidene)amino N- phenylcarbamate (1), an established inhibitor of β-N-acetylglucosaminidases, has been prepared by an improved six-step synthesis from N-acetyl-D- glucosamine.
