87269-98-5

Basic information

• Product Name: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester
• Synonyms: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester
• CAS NO: 87269-98-5
• Molecular Weight: 383.444
• Mol File: 87269-98-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester(87269-98-5)
• EPA Substance Registry System: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester(87269-98-5)

Safety Data

• Hazardous Substances Data: 87269-98-5(Hazardous Substances Data)

Usage

Description

(1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester is a complex organic compound that is an ethyl ester derivative of 4-oxo-4-phenylbutanoic acid. It features an additional methyl and phenyl group, as well as an amino group attached to an ether moiety. Due to its structural similarity to known pharmacologically active compounds, it likely has pharmaceutical applications and may serve as a drug candidate or pharmacological tool in research. However, further research and testing are required to fully understand its properties and potential uses.

Uses

Used in Pharmaceutical Industry:
(1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester is used as a potential drug candidate for its structural similarity to known pharmacologically active compounds. Its specific chemical structure suggests that it may have therapeutic applications, although the exact uses will depend on the results of further research and testing.

Upstream product

• 15121-89-8 ethyl (E)-4-oxo-4-phenyl-2-butenoate 
• 17831-02-6 D-alanine benzyl ester 
• 15121-89-8 ethyl 3-benzoyl acrylate 
• 42854-62-6 L-alanine benzyl ester p-toluenesulfonate 
• 64-67-5 diethyl sulfate 
• 17831-01-5 H-Ala-OBzl 

Downstream Products

• 87269-88-3 2--L-alanyl>-(1S,3S,5S)-2-azabicyclo<3.3.0>octane-3-carboxylic acid benzylester 
• 87333-19-5 Ramipril 
• 87269-99-6 N-[(1S)-1-ethoxycarbonyl-3-phenyl-3-oxopropyl]-L-alanine 
• 82717-96-2 [1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanine 

Relevant articles and documents

Preparation method of N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine

The invention provides a preparation method of N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine. The preparation method comprises the following steps: performing addition reaction on a compound I and a compound II under the action of a first catalyst to obtain an addition product, wherein the first catalyst is selected from a first thiourea compound and/or a urea compound; performing hydrogenation reaction on the addition product to obtain the N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine. The first catalyst (the first thiourea compound and/or the urea compound) can be added to the reaction system, the selectivity of the addition reaction is improved and the separation efficiency of the required product in the addition reaction process is improved, so that the yield of the final product N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine is increased. The method has the advantages of being short in synthesis route, simple in aftertreatment, capable of being applied to industrialized production and the like.

Addition of enantiomerically pure amines to activated olefines II. On the addition to ethyl (E)-4-oxo-4-phenyl-2-butenoate

The addition of (S)-phenethylamine to ethyl (E)-4-oxo-4-phenyl-2-butenoate shows no kinetic selectivity, whereas - according to the b,pl,H-rule the AB-and BB-product are kinetically preferred in the addition of (S)-alanine-isopropylester and -benzylester,