873383-11-0

Basic information

• Product Name: 6-BROMO-1-METHYLPYRIDIN-2(1H)-ONE
• Synonyms: 6-BROMO-1-METHYLPYRIDIN-2(1H)-ONE;6-Bromo-1-methylpyridine-2(1H)one;2(1H)-Pyridinone, 6-broMo-1-Methyl-;6-bromo-1-methylpyridin-2-one;6-Bromo-1-methyl-1,2-dihydropyridin-2-one;6-Bromo-1-methylpyridin-2(1H)
• CAS NO: 873383-11-0
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02
• Mol File: 873383-11-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 287.109°C at 760 mmHg
• Flash Point: 127.439°C
• Appearance: /
• Density: 1.665g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -0.98±0.62(Predicted)
• CAS DataBase Reference: 6-BROMO-1-METHYLPYRIDIN-2(1H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-1-METHYLPYRIDIN-2(1H)-ONE(873383-11-0)
• EPA Substance Registry System: 6-BROMO-1-METHYLPYRIDIN-2(1H)-ONE(873383-11-0)

Safety Data

• Hazardous Substances Data: 873383-11-0(Hazardous Substances Data)

Usage

General Description

6-Bromo-1-methylpyridin-2(1H)-one is a chemical compound with the molecular formula C6H6BrNO. It is a pyridine derivative that is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 6-BROMO-1-METHYLPYRIDIN-2(1H)-ONE is known for its versatility in organic synthesis and can be used as a building block for the production of various biologically active molecules. It is also used in the manufacturing of fine chemicals and other specialty products. The presence of the bromine and methyl groups in the compound enhances its reactivity and makes it a valuable component in the production of diverse chemical compounds.

InChI:InChI=1/C6H6BrNO/c1-8-5(7)3-2-4-6(8)9/h2-4H,1H3

Upstream product

• 19798-81-3 2-Amino-6-bromopyridine 
• 74-88-4 methyl iodide 
• 27992-32-1 6-bromo-2-hydroxypyridine 
• 626-05-1 2,6-Dibromopyridine 
• 1352724-65-2 (4-Fluorophenyl)(3'-hydroxy-1'-(4-methoxybenzyl)-[1,4'-bipiperidin]-4-yl)methanone 
• 27992-32-1 6-bromo-2-pyridone 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 35069-95-5 1-methyl-6-phenylpyridin-2(1H)-one 
• 2766-64-5 2,3,5,6-tetrabromopyridine 
• 626-05-1 2,6-Dibromopyridine 

Relevant articles and documents

OXAAZAQUINAZOLINE-7(8H)-KETONE COMPOUND, PREPARATION METHOD THERFOR AND PHARMACEUTICAL APPLICATION THEREOF

Disclosed are an oxazaazaquinazolin-7(8H)-ketone compound with a selective inhibition effect on KRAS gene mutation and pharmaceutically acceptable salts thereof, stereoisomers, solvent compounds or prodrugs (as shown in formula I or formula II, see the details of the definition to each group in the formulas in the specification), as well as the pharmaceutical composition containing the compound, and the application thereof in preparation of cancer medicine.

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.

BTK INHIBITOR

Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).