87427-66-5

Basic information

• Product Name: 5-(4-chlorophenyl)-3,6-dihydro-2H-1,3,4-thiadiazin-2-one
• CAS NO: 87427-66-5
• Molecular Formula: C₉H₇ClN₂OS
• Molecular Weight: 226.6827
• Mol File: 87427-66-5.mol
• Article Data: 3

Chemical Properties

• Density: 1.5g/cm³
• Refractive Index: 1.699
• CAS DataBase Reference: 5-(4-chlorophenyl)-3,6-dihydro-2H-1,3,4-thiadiazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chlorophenyl)-3,6-dihydro-2H-1,3,4-thiadiazin-2-one(87427-66-5)
• EPA Substance Registry System: 5-(4-chlorophenyl)-3,6-dihydro-2H-1,3,4-thiadiazin-2-one(87427-66-5)

Safety Data

• Hazardous Substances Data: 87427-66-5(Hazardous Substances Data)

Usage

Type

Heterocyclic compound

Ring structure

Contains a thiadiazine ring

Uses

Organic synthesis, medicinal chemistry

Potential biological activities

Anti-inflammatory, anticancer

Potential uses

Insecticide, herbicide

Need for further research

To fully understand its properties and potential uses

Upstream product

• 536-38-9 4-chlorobenzoylmethyl bromide 
• 4468-82-0 O-ethyl hydrazinothioformate 
• 79416-68-5 S-ethyl hydrazinecarbothioate 

Downstream Products

• 531496-54-5 5-(4-Chloro-phenyl)-3-(4-nitro-benzyl)-3,6-dihydro-[1,3,4]thiadiazin-2-one 
• 937169-17-0 5-(4-chlorophenyl)-3-(3-nitrobenzyl)-3,6-dihydro-1,3,4-thiadiazin-2-one 

Relevant articles and documents

Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them

Compounds of formula (I): wherein: m and n represent 1 or 2,A represents a pyrrolyl group,X represents a C(O), S(O) or SO2 group,R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group,R3 and R4, together with the atoms carrying them, form a heterocyclic group,R5 represents a hydrogen atom or an alkyl group,R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.

3, 6-Dihydro-2-Oxo-6H-1,3,4,-Thiadiazine Derivatives

Compounds of the formula I, in which R1, R2, Q and B have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.