874288-85-4

Basic information

• Product Name: 4-Thiazolecarboxylic acid, 5-[(1-phenylethyl)amino]-, ethyl ester
• CAS NO: 874288-85-4
• Molecular Formula: C14H16N2O2S
• Molecular Weight: 276.359
• Mol File: 874288-85-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Thiazolecarboxylic acid, 5-[(1-phenylethyl)amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolecarboxylic acid, 5-[(1-phenylethyl)amino]-, ethyl ester(874288-85-4)
• EPA Substance Registry System: 4-Thiazolecarboxylic acid, 5-[(1-phenylethyl)amino]-, ethyl ester(874288-85-4)

Safety Data

• Hazardous Substances Data: 874288-85-4(Hazardous Substances Data)

Upstream product

• 2999-46-4 Ethyl isocyanoacetate 
• 24277-44-9 (1-isothiocyanato-ethyl)-benzene 

Downstream Products

• 874288-86-5 5-(1-phenyl-ethylamino)-thiazole-4-carboxylic acid 

Relevant articles and documents

PHARMACEUTICAL COMPOUNDS

The invention provides a compound for use in the prophylaxis or treatment of a disease state or condition mediated by a cyclin dependent kinase, the compound having the formula (I): (I) and salts, tautomers, N-oxides or solvates thereof; wherein A is a bond, C=O, NRg(C=O) or O(C=O) wherein Rg is hydrogen or C1-4 hydrocarbyl optionally substituted by hydroxy or C1-4 alkoxy; Y is a bond or an alkylene chain of 1, 2 or 3 carbon atoms in length; Q is S or CR2; J is S or CH; provided that one of Q and J is S, and the other of Q and J is not S; when Q is S, there is a double bond between the ring carbon atoms “a” and “b” and a double bond between the ring nitrogen N and J; and when J is S, there is a double bond between Q and the ring carbon atom “a” and a double bond between the ring nitrogen N and the ring carbon atom “b”; and R1 to R4 are as defined in the claims.