874662-43-8

Basic information

• Product Name: Thiourea, N-[(1S,2S)-2-aminocyclohexyl]-N'-[(1R)-1-phenylethyl]-
• Synonyms: 1-((1S,2S)-2-NH2-cyclohexyl)-3-((R)-1-phenylethyl)thiourea;1-((1S,2S)-2-Amino-cyclohexyl)-3-((R)-1-phenyl-ethyl)-thiourea;1-[(1S,2S)-2-aminocyclohexyl]-3-[(R)-1-phenylethyl]thiourea
• CAS NO: 874662-43-8
• Molecular Formula: C15H23N3S
• Molecular Weight: 277.42800
• Mol File: 874662-43-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 62 - 63 °C
• Boiling Point: 407.3±55.0 °C(Predicted)
• Density: 1.13±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Thiourea, N-[(1S,2S)-2-aminocyclohexyl]-N'-[(1R)-1-phenylethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-[(1S,2S)-2-aminocyclohexyl]-N'-[(1R)-1-phenylethyl]-(874662-43-8)
• EPA Substance Registry System: Thiourea, N-[(1S,2S)-2-aminocyclohexyl]-N'-[(1R)-1-phenylethyl]-(874662-43-8)

Safety Data

• Hazardous Substances Data: 874662-43-8(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 21436-03-3 (S,S)-1,2-diaminocyclohexane 
• 24277-44-9 (R)-(1-isothiocyanatoethyl)benzene 

Downstream Products

• 1425943-93-6 C₂₆H₄₁N₅O₄S 
• 1425943-96-9 C₁₆H₂₅N₅S 
• 1425943-95-8 C₂₁H₃₃N₅O₂S*C₂HF₃O₂ 
• 887780-44-1 C₂₈H₃₆N₄O₃S 

Relevant articles and documents

Synthesis and evaluation of new guanidine-thiourea organocatalyst for the nitro-Michael reaction: Theoretical studies on mechanism and enantioselectivity

A new guanidine-thiourea organocatalyst has been developed and applied as bifunctional organocatalyst in the Michael addition reaction of diethyl malonate to trans-β-nitrostyrene. Extensive DFT calculations, including solvent effects and dispersion correc

Asymmetric organocatalysis with novel chiral thiourea derivatives: Bifunctional catalysts for the Strecker and nitro-Michael reactions

Novel bifunctional organocatalysts bearing both a thiourea moiety and an imidazole group on a chiral scaffold were synthesized and applied to the Strecker synthesis and nitro-Michael reaction. The addition of acetone to nitroolefins in the presence of these novel bifunctional organocatalysts gave enantioselectivities (up to 87 % ee) that are superior to those generated by the proline and/or homo-proline tetrazole catalysts described in the literature. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.