874820-54-9

Basic information

• Product Name: Carbamic acid, [trans-4-[[(2-chloro-5-nitro-4-pyrimidinyl)amino]methyl]cyclohexyl]-, 1,1-dimethylethyl ester
• CAS NO: 874820-54-9
• Molecular Formula: C16H24ClN5O4
• Molecular Weight: 385.851
• Mol File: 874820-54-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [trans-4-[[(2-chloro-5-nitro-4-pyrimidinyl)amino]methyl]cyclohexyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [trans-4-[[(2-chloro-5-nitro-4-pyrimidinyl)amino]methyl]cyclohexyl]-, 1,1-dimethylethyl ester(874820-54-9)
• EPA Substance Registry System: Carbamic acid, [trans-4-[[(2-chloro-5-nitro-4-pyrimidinyl)amino]methyl]cyclohexyl]-, 1,1-dimethylethyl ester(874820-54-9)

Safety Data

• Hazardous Substances Data: 874820-54-9(Hazardous Substances Data)

Upstream product

• 177583-27-6 tert-butyl ((1r,4r)-4-(aminomethyl)cyclohexyl)carbamate 
• 49845-33-2 2,4-Dichloro-5-nitropyrimidine 

Relevant articles and documents

Pyrimidine derivatives useful as inhibitors of PKC-theta

Disclosed are novel compounds of formula (I): wherein X, Y, R1, R2 and R3 are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and type II diabetes. This invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.