875340-81-1

Basic information

• Product Name: 3-[(tert-ButyldiMethylsilanyl)oxy]azetidine
• Synonyms: 3-[(tert-ButyldiMethylsilanyl)oxy]azetidine;3-[(tert-butyldimethylsilyl)oxy]azetidine
• CAS NO: 875340-81-1
• Molecular Formula: C₉H₂₁NOSi
• Molecular Weight: 187.35464
• Mol File: 875340-81-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-[(tert-ButyldiMethylsilanyl)oxy]azetidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(tert-ButyldiMethylsilanyl)oxy]azetidine(875340-81-1)
• EPA Substance Registry System: 3-[(tert-ButyldiMethylsilanyl)oxy]azetidine(875340-81-1)

Safety Data

• Hazardous Substances Data: 875340-81-1(Hazardous Substances Data)

Usage

General Description

3-[(tert-ButyldiMethylsilanyl)oxy]azetidine is a chemical compound that belongs to the class of azetidines, which are four-membered ring compounds containing nitrogen at the first position. This specific compound contains a silanol group attached to the azetidine ring, which is protected by a tert-butyldimethylsilyl (TBDMS) group. The TBDMS group is commonly used as a protecting group in organic synthesis to prevent unwanted reactions with certain functional groups. 3-[(tert-ButyldiMethylsilanyl)oxy]azetidine has potential applications in organic synthesis and as a building block for the synthesis of more complex organic molecules.

Upstream product

• 391910-20-6 3-((tert-butyldimethylsilyl)oxy)-1-(diphenylmethyl)azetidine 
• 1434650-42-6 benzyl 3-[(tert-butyldimethylsilyl)oxy]azetidine-1-carboxylate 
• 45347-82-8 azetidine-3-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 18621-18-6 azetion-3-ol hydrochloride 
• 875340-80-0 tert-butyl 3-(tert-butyldimethylsilyloxy)azetidine-1-carboxylate 

Downstream Products

• 1443670-66-3 C₁₉H₃₁NO₂Si 
• 1446008-01-0 (S)-N-(1-{4-[3-(tert-butyl-dimethyl-silanyloxy)-azetidin-1-yl]-phenyl}-ethyl)-acetamide 
• 1427064-86-5 [3-(t-butyldimethylsilanyloxy)azetidin-1-yl]carbamic acid t-butyl ester 
• 105-07-7 4-cyanobenzaldehyde 
• 1258855-85-4 5-(3-{3-[2-(3-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-1-azetidinyl)-2-oxoethyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl}-1,2,4-oxadiazol-5-yl)-2-[(1-methylethyl)oxy]benzonitrile 

Relevant articles and documents

SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS

The application relates to a compound of Formula (I') or (I), or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of thyroid hormone receptors, a pharmaceutical composition comprising a compound of Formula (I') or (I), and a method of treating or preventing a disease or disorder regulated by thyroid hormone.

AZABENZIMIDAZOLE DERIVATIVES AS PI3K BETA INHIBITORS

The present invention relates to azabenzimidazole derivatives of Formula (I) (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active 10 ingredient as well as the use of said compounds as a medicament.

ANTI-ESTROGENIC COMPOUNDS

The present disclosure provides a compound of Formula I: or a pharmaceutically acceptable salt wherein X, R1-R8, Y1-Y5, m, n, p, and q are defined herein. The novel 2H-chromene compounds are useful for the modul