87628-94-2

Basic information

• Product Name: 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1-(phenylmethyl)-
• CAS NO: 87628-94-2
• Molecular Formula: C21H20FN3O
• Molecular Weight: 349.408
• Mol File: 87628-94-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1-(phenylmethyl)-(87628-94-2)
• EPA Substance Registry System: 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1-(phenylmethyl)-(87628-94-2)

Safety Data

• Hazardous Substances Data: 87628-94-2(Hazardous Substances Data)

Usage

Core structure

pyrazolo[4,3-c]pyridine

Acetyl group

at position 5

Tetrahydro structure

4,5,6,7

Fluorophenyl group

at position 3

Phenylmethyl group

at position 1

Potential uses

pharmaceuticals, agrochemicals, material science

Safety

handle with caution and follow proper protocols due to complexity and potential reactivity.

Upstream product

• 87642-26-0 1-Acetyl-3-(4-fluoro-benzoyl)-piperidin-4-one 
• 55459-60-4 1-(4-(morpholin-4-yl)-3,6-dihydro-2H-pyridin-1-yl)ethanone 
• 32161-06-1 1-acetyl-4-piperidinone 

Downstream Products

• 87642-38-4 3-(4-fluorophenyl)-1-(phenylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo<4,3-c>pyridine hydrochloride 

Relevant articles and documents

Substituted 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridines, Their Use as Medicament, and Pharmaceutical Preparations Comprising Them

The invention relates to substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula (I) act on the TASK-1 potassium channel. The compounds are particularly suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.

Synthesis, in Vitro 3H>Prazosin Displacement, and in Vivo Activity of 3-Aryl-4,5,6,7-tetrahydropyrazolopyridines, a New Class of Antihypertensive Agents

A series of a new 3-aryl-4,5,6,7-tetrahydropyrazolopyridines was synthesized and screened for in vitro 3H>prazosin displacement activity.The results correlated well with their antihypertensive activity in spontaneous hypertensive rats.