87687-03-4

Basic information

• Product Name: RESORUFIN PENTYL ETHER
• Synonyms: 7-PENTOXYRESORUFIN;7-PENTYLOXY-3H-PHENOXAZIN-3-ONE;7-PENTYLOXY-3-PHENOXAZONE;RESORUFIN PENTYL ETHER;PENTOXYRESORUFIN;O(7)-PENTYLRESORUFIN;O(7)-PENTYLRESORUFIN, FOR FLUORESCENCE;O(7)-PENTYLRESORUFIN FOR FLUORESCENCE 98+%
• CAS NO: 87687-03-4
• Molecular Formula: C17H17NO3
• Molecular Weight: 283.32
• Product Categories: Fluorescent Labels & Indicators
• Mol File: 87687-03-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 151-153°C
• Boiling Point: 423.6°C at 760 mmHg
• Flash Point: 183.4°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 2.21E-07mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: 2-8°C
• Solubility: acetonitrile: 0.25 mg/mL, clear, brown-orange
• BRN: 8394939
• CAS DataBase Reference: RESORUFIN PENTYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: RESORUFIN PENTYL ETHER(87687-03-4)
• EPA Substance Registry System: RESORUFIN PENTYL ETHER(87687-03-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 87687-03-4(Hazardous Substances Data)

Usage

Description

RESORUFIN PENTYL ETHER is a synthetic compound that serves as a fluorimetric substrate and a fluorescent indicator of Cytochrome P 450 activity. It is utilized in various applications across different industries, primarily for its ability to measure the induction of cytochrome(s) P-450 and study the effects of certain extracts on mouse hepatic cytochrome P450 enzymes.

Uses

Used in Research and Development:
RESORUFIN PENTYL ETHER is used as a fluorimetric substrate for the dealkylation of pentoxyresorufin, providing a rapid and sensitive assay for measuring the induction of cytochrome(s) P-450. This application is crucial in understanding the effects of various substances on the activity of these enzymes, which play a significant role in drug metabolism and detoxification processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, RESORUFIN PENTYL ETHER is used as a substrate to study the effects of Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes. This research helps in evaluating the potential interactions between the extract and the enzymes, which can be vital for drug development and understanding the mechanisms of action.
Used in Analytical Chemistry:
As a fluorescent indicator of Cytochrome P 450 activity, RESORUFIN PENTYL ETHER is employed in analytical chemistry to monitor and measure the activity of these enzymes. This is particularly useful in assessing the efficiency of drug metabolism and the potential for drug-drug interactions, ensuring the safety and efficacy of medications.

Biochem/physiol Actions

Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.

InChI:InChI=1/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3