87726-93-0

Basic information

• Product Name: (2S,1'R)-N-(1-Phenylethyl)alanin-ethylester
• CAS NO: 87726-93-0
• Molecular Weight: 221.299
• Mol File: 87726-93-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,1'R)-N-(1-Phenylethyl)alanin-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,1'R)-N-(1-Phenylethyl)alanin-ethylester(87726-93-0)
• EPA Substance Registry System: (2S,1'R)-N-(1-Phenylethyl)alanin-ethylester(87726-93-0)

Safety Data

• Hazardous Substances Data: 87726-93-0(Hazardous Substances Data)

Upstream product

• 687-47-8 (S)-Ethyl lactate 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 84028-88-6 ethyl (S)-lactate triflate 
• 30365-54-9 ethyl (S)-2-bromopropionate 

Relevant articles and documents

Amino Acids, 4 - Enantioselective Synthesis of N-Substituted α-Amino Carboxylic Acids from α-Hydroxy Carboxylic Acids

With primary and secondary amines, the (S)-α-(trifluoromethylsulfonyloxy) carboxylates (S)-3 afford in an SN2 reaction the N-substituted (R)-α-amino carboxylates (R)-5, (R)-9, and (R)-12, resp.The rates of α-substituted ethyl propionates decrease in the order of the substituents triflate (3a) >> bromide (8a) > mesylate (7a) >= tosylate (7b) > chloride (8b); in the reactions with amines, decreasing reactivity affords increasing racemisation and elimination as a consequence of the more drastic conditions which are required