87776-80-5

Basic information

• Product Name: 2-(3,4-DIMETHYLPHENYL)ETHANOL
• Synonyms: 2-(3,4-DIMETHYLPHENYL)ETHANOL
• CAS NO: 87776-80-5
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.22
• Mol File: 87776-80-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 109-110 °C(Press: 3 Torr)
• Appearance: /
• Density: 0.993 g/cm3(Temp: 23 °C)
• PKA: 14.98±0.10(Predicted)
• CAS DataBase Reference: 2-(3,4-DIMETHYLPHENYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DIMETHYLPHENYL)ETHANOL(87776-80-5)
• EPA Substance Registry System: 2-(3,4-DIMETHYLPHENYL)ETHANOL(87776-80-5)

Safety Data

• Hazardous Substances Data: 87776-80-5(Hazardous Substances Data)

Upstream product

• 75-21-8 oxirane 
• 89980-68-7 3,4-dimethylphenylmagnesium bromide 
• 583-71-1 4-bromo-o-xylene 
• 17283-16-8 3,4-dimethylphenylacetic acid 
• 95-47-6 o-xylene 
• 102-46-5 4-(chloromethyl)-1,2-dimethylbenzene 
• 3020-06-2 3,4-dimethylphenylacetonitrile 
• 57486-71-2 2-(3,4-dimethylphenyl)acetic acid methyl ester 
• 105401-66-9 acetic acid-(3,4-dimethyl-phenethyl ester) 

Downstream Products

• 103323-56-4 2-(3',4'-dimethylphenyl)ethyl bromide 
• 105907-98-0 5-<3,4-Dimethyl-phenyl>-3-thia-valeriansaeurechlorid 
• 110530-91-1 2,2'-Bis-<3,4-dimethyl-phenyl>-diethylsulfid 
• 105972-06-3 5-<3,4-Dimethyl-phenyl>-3-thia-valeriansaeureamid 
• 857169-78-9 5-<3,4-Dimethyl-phenyl>-3-thia-valeriansaeure 
• 103440-42-2 2-<3,4-Dimethyl-phenyl>-ethylmercaptan 
• 503597-14-6 N-[4-(3,4-dimethylphenyl)-2-(pivaloyloxymethyl)butyl]-N'-[3-methoxy-4-(methoxymethoxy)benzyl]thiourea 
• 503597-34-0 N-[4-(3,4-dimethylphenyl)-1-pivaloyloxy-2-butyl]-N'-[3-methoxy-4-(methoxymethoxy)benzyl]thiourea 
• 503597-26-0 ethyl 4-(3,4-dimethylphenyl)-2-[(diphenylmethylene)amino]butanoate 
• 503597-31-7 2-[(tert-butoxycarbonyl)amino]-4-(3,4-dimethylphenyl)butyl pivalate 
• 503597-28-2 ethyl 2-(tert-butoxycarbonylamino)-4-(3,4-dimethylphenyl)butanoate 
• 503597-11-3 2-(azidomethyl)-4-(3,4-dimethylphenyl)butyl pivalate 
• 503597-29-3 tert-butyl N-[3-(3,4-dimethylphenyl)-1-(hydroxymethyl)propyl]carbamate 
• 503598-02-5 2,2-dimethyl-propionic acid 2-aminomethyl-4-(3,4-dimethyl-phenyl)-butyl ester 

Relevant articles and documents

Catalytic Cyclization of o-Alkynyl Phenethylamines via Osmacyclopropene Intermediates: Direct Access to Dopaminergic 3-Benzazepines

A novel osmium-catalyzed cyclization of o-alkynyl phenethylamines to give 3-benzazepines is reported. The procedure allows the straightforward preparation of a broad range of dopaminergic 3-benzazepine derivatives. Mechanistic investigations revealed that the process takes place via osmacyclopropene intermediates, which were isolated and characterized by X-ray crystallography.

Muscarinic receptor antagonists

Muscarinic receptor antagonists of formula (I), and their pharmaceutically acceptable salts, wherein Y is --CH 2 --, --(CH 2) 2 --, --CH 2 O--, --(CH 2) 2 O-- or --CH 2 S--; R is --CH or --CONH 2 ; and R 1 is a group of formula (a), where R 2 and R 3 are each independently H, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, --(CH 2) n OH, halo, trifluoromethyl, cyano, --(CH 2) n NR 4 R 5, --CO(C 1 -C 4 alkyl), --OCO(C 1 -C 4 alkyl), --CH(OH)(C 1 -C 4 alkyl), --C(OH)(C 1 -C 4 alkyl 2, --SO 2 NH 2, --(CH 2) n CONR 6 R 7 or --(CH 2) n COO(C 1 -C 4 alkyl); R 4 is H or C 1 -C 4 alkyl; R 5 is H, C 1 -C 4 alkyl or C 1 -C 4 alkysulphonyl; R 6 and R 7 are each independently H or C 1 -C 4 alkyl; and n is 0, 1 or 2. The compounds are particularly useful in treating irritable bowel syndrome.