87797-89-5

Basic information

• Product Name: (R)-α,α,5,6-Tetramethyl-1,2,3,4-tetrahydronaphthalene-2-methanol
• Synonyms: (R)-1,2,3,4-Tetrahydro-α,α,5,6-tetramethyl-2-naphthalenemethanol;(R)-α,α,5,6-Tetramethyl-1,2,3,4-tetrahydronaphthalene-2-methanol;Occidol-2
• CAS NO: 87797-89-5
• Molecular Formula: C15H22O
• Molecular Weight: 218.33458
• Mol File: 87797-89-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-α,α,5,6-Tetramethyl-1,2,3,4-tetrahydronaphthalene-2-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-α,α,5,6-Tetramethyl-1,2,3,4-tetrahydronaphthalene-2-methanol(87797-89-5)
• EPA Substance Registry System: (R)-α,α,5,6-Tetramethyl-1,2,3,4-tetrahydronaphthalene-2-methanol(87797-89-5)

Safety Data

• Hazardous Substances Data: 87797-89-5(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 116987-92-9 ethyl 5,6-dimethyl-1,2,3,4-tetrahydro-2-naphthoate 
• 917-54-4 methyllithium 
• 332075-10-2 5,6-dimethyl-1,2,3,4-tetrahydro-2-naphthoic acid 
• 13621-30-2 4-(2,3-dimethylphenyl)butanoic acid 
• 32281-65-5 5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-1-one 
• 116987-93-0 5,6-Dimethyl-1-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis of (±)-7,8- and 5,6-dimethyl-2-(2-hydroxyisopropyl) tetralins

7,8-Dimethyl-l-tetralone 4 on sodium borohydride reduction followed by Vilsmeier-Haack reaction furnishes 7, 8-dimethyl-3,4-dihydro-2-naphthaldehyde 10. Reduction of 10 followed by oxidation with Jones reagent yields 7, 8-dimethyl-1,2,3,4-tetrahydro-2-naphthoic acid 12 which on treatment with excess of methyllithium affords 7, 8-dimethyl-2-(2-hydroxyisopropyl) tetralin 2. 5,6-dimethyl-l-tetralone 5 is converted into the 5,6-dimethyl-2-(2-hydroxyisopropyl)tetralin 3 by following similar set of reactions as described above.