878194-94-6

Basic information

• Product Name: 2-Chloro-3-cyano-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine
• Synonyms: 2-Chloro-3-cyanopyridine-4-boronic Acid Pinacol Ester;2-Chloro-3-cyano-4-pyridinylboronic acid pinacol ester;2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile;2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile
• CAS NO: 878194-94-6
• Molecular Formula: C₁₂H₁₄BClN₂O₂
• Molecular Weight: 264.52
• Mol File: 878194-94-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 100-101℃
• Boiling Point: 410.9°C at 760 mmHg
• Flash Point: 202.3°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 5.81E-07mmHg at 25°C
• Refractive Index: 1.521
• Storage Temp.: ?20°C
• CAS DataBase Reference: 2-Chloro-3-cyano-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-cyano-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine(878194-94-6)
• EPA Substance Registry System: 2-Chloro-3-cyano-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine(878194-94-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 2
• Hazardous Substances Data: 878194-94-6(Hazardous Substances Data)

Usage

General Description

2-Chloro-3-cyano-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine is a complex chemical compound. It belongs to the class of compounds named organoboron compounds, specifically those containing boric acid or its derivatives. The unique part of this compound is its boronic ester group, which is the 4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl moiety. 2-Chloro-3-cyano-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine also contains a pyridine ring, which is a six-membered aromatic ring with a nitrogen atom, contributing to its unique properties. Additionally, it has a chloro group and a cyano group attached to the pyridine ring. It does not have a significant commercial or industrial use, but is often used in research and laboratory settings, such as in the field of organic synthesis.

InChI:InChI=1/C12H14BClN2O2/c1-11(2)12(3,4)18-13(17-11)9-5-6-16-10(14)8(9)7-15/h5-6H,1-4H3

Upstream product

• 878194-88-8 C₆H₄BClN₂O₂ 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 886362-03-4 2-chloro-4-(p-tolyl)nicotinonitrile 
• 1644384-66-6 methyl 4-(2-chloro-3-cyanopyridin-4-yl)benzoate 

Relevant articles and documents

AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME

Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME

Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are the methods for treating of diseases associated with an amyloid or amyloid like proteins.