878199-35-0Relevant articles and documents
Multi-Step synthesis by using modular flow reactors: The preparation of Yne-Ones and their use in heterocycle synthesis
Baxendale, Ian R.,Schou, Seren C.,Sedelmeier, Joerg,Ley, Steven V.
supporting information; experimental part, p. 89 - 94 (2010/03/03)
"Chemical Equation Presented" Multi-step in flow: The palladium-catalysed acylation of terminal alkynes for the synthesis of yne-ones as well as their further transformation to various heterocycles in a continuous-flow mode is presented. Furthermore, an extension of the simple flow configuration that allows for easy batch splitting and the generation of a heterocyclic library is described (see scheme).