878289-33-9

Basic information

• Product Name: 2-(Piperidin-1-ylmethyl)phenylboronic acid
• Synonyms: 2-(Piperidin-1-ylmethyl)phenylboronic acid;[2-(1-piperidylmethyl)phenyl]boronic acid;[2-(piperidinomethyl)phenyl]boronic acid
• CAS NO: 878289-33-9
• Molecular Formula: C12H18BNO2
• Molecular Weight: 219.08782
• Product Categories: Boronate Ester;Boronic Acid;Potassium Trifluoroborate
• Mol File: 878289-33-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(Piperidin-1-ylmethyl)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Piperidin-1-ylmethyl)phenylboronic acid(878289-33-9)
• EPA Substance Registry System: 2-(Piperidin-1-ylmethyl)phenylboronic acid(878289-33-9)

Safety Data

• Hazardous Substances Data: 878289-33-9(Hazardous Substances Data)

Usage

General Description

2-(Piperidin-1-ylmethyl)phenylboronic acid, also known as PIPERONYL BORONIC ACID, is an organic compound with the chemical formula C12H17BNO2. It is a boronic acid derivative that contains a piperidine ring and a phenyl group attached to a boronic acid functional group. 2-(Piperidin-1-ylmethyl)phenylboronic acid is used as a building block in organic synthesis, particularly in the development of pharmaceuticals and other biologically active molecules. It is also used in the preparation of boronic acid-based catalysts and materials for chemical sensing and molecular recognition applications. Additionally, this chemical has been investigated for its potential anti-tumor and anti-inflammatory properties.

Upstream product

• 110-89-4 piperidine 
• 40138-16-7 2-formylbenzene boronic acid 

Relevant articles and documents

Amination-reduction reaction as simple protocol for potential boronic molecular receptors. Insight in supramolecular structure directed by weak interactions

The synthesis of the potential molecular receptors in the amination-reduction reaction has been investigated within the model system comprising (2-formylphenyl)boronic acid and morpholine. The 3-amine substituted benzoxaborole was identified to be the intermediate of the synthesis and the unsubstituted benzoxaborole as the by-product resulting from reduction of the starting material. The insight into the reactivity of the starting materials as well as the intermediate benzoxaborole enabled significant rise in the yield of 2-(aminomethyl) phenylboronic acids synthesis. The solid state structure of 2-(piperidylmethyl)phenylboronic acid has been re-determined, and the description of the molecule and the crystal is given. The supramolecular layer structure directed by the weak C-H...O and C-H...π interactions was identified and scrutinized based on the geometry and Hirshfeld surface analyses. Versita Sp. z o.o.