87866-15-7

Basic information

• Product Name: Gal-β1,3[GlcNAc-β1,6]-GalNAc-α1-OBn
• CAS NO: 87866-15-7
• Molecular Weight: 676.672
• Mol File: 87866-15-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Gal-β1,3[GlcNAc-β1,6]-GalNAc-α1-OBn(CAS DataBase Reference)
• NIST Chemistry Reference: Gal-β1,3[GlcNAc-β1,6]-GalNAc-α1-OBn(87866-15-7)
• EPA Substance Registry System: Gal-β1,3[GlcNAc-β1,6]-GalNAc-α1-OBn(87866-15-7)

Safety Data

• Hazardous Substances Data: 87866-15-7(Hazardous Substances Data)

Upstream product

• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 117181-30-3 benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranoside 
• 90754-57-7 benzyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1<*>3)-2-acetamido-2-deoxy-α-D-galactopyranoside 
• 117182-56-6 benzyl 2-acetamide-4,6-O-benzylidene-2-deoxy-α-D-galactopyranoside 
• 10378-06-0 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline 
• 3554-93-6 benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside 
• 16426-39-4 uridine diphosphate N-acetylglucosamine 
• 528-04-1 uridine 5'-diphospho-N-acetylglucosamine 
• 5965-66-2 LACTOSE 
• 90805-11-1 benzyl 2-acetamido-<6-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)>-2-deoxy-α-D-galactopyranoside 

Downstream Products

• 85054-31-5 GlcNAc-β1,6-GalNAc-α1-OBn 

Relevant articles and documents

Optimization of the enzymatic synthesis of O-glycan core 2 structure by use of a genetic algorithm

The enzymatic synthesis of Gal-β1,3[GlcNAc-β1,6]-GalNAc-α1-OBn (core 2-Bn) using a multi-enzyme system consisting of a β-galactosidase (EC 3.2.1.23) from bovine testes and a recombinant core 2 β1,6-GlcNAc transferase (C2GnT, EC 2.4.1.102) was empirically optimized by the use of a genetic algorithm. After variation of seven relevant parameters and performance of 56 experiments, two local maxima regarding the selection criterias could be found after four generations of optimization. The selectivity of core 2-Bn formation showed values up to 90%.

Synthetic mucin fragments: benzyl 2-acetamido-6-O-(2-acetamido-2-deoxy-beta- D-glucopyranosyl)-2-deoxy-3-O-beta-D-galactopyranosyl-alpha-D- galactopyranoside and benzyl 2-acetamido-6-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)- 3-O-[6-O-(2-acetamido-2-d

Glycosylation of benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-alpha-D- galactopyranoside with 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl bromide, catalyzed by mercuric cyanide, afforded benzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-3- O-(2,3,4,6-tetra