879015-30-2

Basic information

• Product Name: 1,4-Benzenedicarboxylic acid, mono[[(2S,5R)-5-(1,6-dihydro-6-oxo-9H-purin-9-yl)tetrahydro-2-furanyl] methyl] ester
• CAS NO: 879015-30-2
• Molecular Formula: C18H16N4O6
• Molecular Weight: 384.348
• Mol File: 879015-30-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4-Benzenedicarboxylic acid, mono[[(2S,5R)-5-(1,6-dihydro-6-oxo-9H-purin-9-yl)tetrahydro-2-furanyl] methyl] ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenedicarboxylic acid, mono[[(2S,5R)-5-(1,6-dihydro-6-oxo-9H-purin-9-yl)tetrahydro-2-furanyl] methyl] ester(879015-30-2)
• EPA Substance Registry System: 1,4-Benzenedicarboxylic acid, mono[[(2S,5R)-5-(1,6-dihydro-6-oxo-9H-purin-9-yl)tetrahydro-2-furanyl] methyl] ester(879015-30-2)

Safety Data

• Hazardous Substances Data: 879015-30-2(Hazardous Substances Data)

Upstream product

• 100-21-0 terephthalic acid 
• 69655-05-6 Dideoxyinosine 

Relevant articles and documents

COMPOUNDS

The invention provides a water-soluble prodrug compound comprising a therapeutically effective moiety coupled via a metabolically cleavable bond to a protein binding moiety, wherein said therapeutically effective moiety has an anticancer, antiinflammatory, antiinfective or antipain effect, said protein binding moiety binds non-covalently to blood proteins, and the protein binding of said compound is at least 100 % higher than that of the therapeutically effective moiety itself, with the exclusion of (i) the monoester of gemcitabine with azelaic acid, (ii) the monoester of dideoxycytidine with 1,12-dodecanedicarboxylic acid, (iii) 2-amino-l,9-dihydro-9(2'-(1-(10-acetyl-decanoyloxy)ethoxymethyl))-guanine, (iv) 5'-cytarabine monoester with 1,4-phenylene diacetic acid, (v) the monoester of metronidazole with 1,4-butanedicarboxylic acid, and (vi) the monoester of metronidazole with 1,6-phenylene diacetic acid; and pre-prodrugs metabolizable thereto.