87904-84-5

Basic information

• Product Name: 2H-1,4-Thiazin-3(4H)-one,2-hydroxy-4-(1-methylethyl)-(9CI)
• Synonyms: 2H-1,4-Thiazin-3(4H)-one,2-hydroxy-4-(1-methylethyl)-(9CI)
• CAS NO: 87904-84-5
• Molecular Formula: C7H11NO2S
• Molecular Weight: 173.23274
• Product Categories: ISOPROPYL
• Mol File: 87904-84-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-1,4-Thiazin-3(4H)-one,2-hydroxy-4-(1-methylethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,4-Thiazin-3(4H)-one,2-hydroxy-4-(1-methylethyl)-(9CI)(87904-84-5)
• EPA Substance Registry System: 2H-1,4-Thiazin-3(4H)-one,2-hydroxy-4-(1-methylethyl)-(9CI)(87904-84-5)

Safety Data

• Hazardous Substances Data: 87904-84-5(Hazardous Substances Data)

Upstream product

• 82912-51-4 2-m-chlorobenzoyloxy-4-isopropyl-2H-1,4-thiazin-3-one 
• 87904-92-5 2-chloro-4-isopropyl-2H-1,4-thiazin-3-one 

Downstream Products

• 85331-46-0 2-(4-Dimethylamino-phenyl)-4-isopropyl-4H-[1,4]thiazin-3-one 
• 85331-44-8 2-etoxy-4-isopropyl-2H-1,4-thiazin-3-one 
• 87904-90-3 2-(4-Hydroxy-phenyl)-4-isopropyl-4H-[1,4]thiazin-3-one 
• 82409-32-3 Benzoic acid 4-isopropyl-3-oxo-3,4-dihydro-2H-[1,4]thiazin-2-yl ester 

Relevant articles and documents

SYNTHESIS AND REACTIONS OF HALO DERIVATIVES OF 4-ISOPROPYL-2H-1,4-THIAZIN-3-ONE

Reaction of 4-isopropyl-2H-1,4-thiazin-3-one 1 (R=i-Pr) with N-chloro- and N-bromosuccinimide occurred exclusively at the 6-position to give 6-chloro and 6-bromo derivatives of 1 (R=i-Pr), respectively, in high yield, in sharp contrast to the 2-aroyloxylation by benzoyl peroxide or m-chloroperbenzoic acid reported earlier.Reaction of 1 (R=i-Pr) with methanesulfonyl chloride in the presence of aluminum chloride afforded an addition compound, 4-isopropyl-5,6-dichloro-1,4-tetrahydrothiazin-3-one.The 2-chloro derivative 6 of 1 (R=i-Pr) was successfully prepared by hydrolysis of the 2-m-chlorobenzoyloxy derivative of 1 (R=i-Pr) followed by treatment with thionyl chloride.Derivative 6 reacted readily under mild conditions with water, alcohols, thiols, ammonia and amines to give various 2-substituted compounds of 1 (R=i-Pr).With phenol as a nucleophile, 1 (R=i-Pr) reacted exclusively at the para position.Reaction at carbon atoms also occurred with N,N-dimethylaniline and 2,6-xylidine.