87954-23-2

Basic information

• Product Name: Methanone, phenyl[1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrrol-2-yl]-
• CAS NO: 87954-23-2
• Molecular Formula: C17H23NO2Si
• Molecular Weight: 301.461
• Mol File: 87954-23-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methanone, phenyl[1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrrol-2-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, phenyl[1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrrol-2-yl]-(87954-23-2)
• EPA Substance Registry System: Methanone, phenyl[1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrrol-2-yl]-(87954-23-2)

Safety Data

• Hazardous Substances Data: 87954-23-2(Hazardous Substances Data)

Upstream product

• 7697-46-3 phenyl(1H-pyrrol-2-yl)methanone 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 87954-20-9 1-<<(β-trimethylsilyl)ethoxy>methyl>pyrrole 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Preparation of 2-substituted pyrroles and indoles by regioselective alkylation and deprotection of 1-(2-trimethylsilyllethoxymethyl)pyrrole and 1-(2-trimethylsulylethoxymethyl) indole

After N-alkylation of pyrrole and indole with 2-trimethylsilylethoxymethyl chloride the products of the reaction could be regioselectively deprotonated with n-butyllithium at the 2-position.Reaction of the resulting anions with acid chlorides, lactones, silyl chlorides or aldehydes gave addition products, some of which were deprotected to the parent pyrrole or indole using anhydrous tetra-n-butylammonium fluoride.