880082-21-3

Basic information

• Product Name: 2-(4-cyano-phenyl)-cyclohex-1-enecarboxylic acid methyl ester
• CAS NO: 880082-21-3
• Molecular Weight: 241.29
• Mol File: 880082-21-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-cyano-phenyl)-cyclohex-1-enecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-cyano-phenyl)-cyclohex-1-enecarboxylic acid methyl ester(880082-21-3)
• EPA Substance Registry System: 2-(4-cyano-phenyl)-cyclohex-1-enecarboxylic acid methyl ester(880082-21-3)

Safety Data

• Hazardous Substances Data: 880082-21-3(Hazardous Substances Data)

Upstream product

• 93493-95-9 2-{[(trifluoromethyl)sulfonyl]oxy}cyclohex-1-enecarboxylic acid methyl ester 
• 126747-14-6 4-cyanophenylboronic acid 

Downstream Products

• 864934-71-4 2-(4-aminomethyl-phenyl)-cyclohex-1-enecarboxylic acid methyl ester 
• 864934-58-7 2-{4-[(4-methyl-3-nitro-pyridin-2-ylamino)-methyl]-phenyl}-cyclohex-1-enecarboxylic acid methyl ester 

Relevant articles and documents

Bradykinin B1 antagonists: SAR studies in the 2,3-diaminopyridine series

SAR study of the biphenyl region of 2,3-diaminopyridine bradykinin B 1 antagonists was investigated with non-aromatic carbo- and heterocyclic rings. A piperidine ring was found to be a good replacement for the proximal phenyl ring while replacement of the distal phenyl was optimal with a cyclohexyl group leading to a dramatic improvement in affinity for the B 1 receptor.