88018-07-9

Basic information

• Product Name: 2-Butenoic acid, 4-(2-formylphenoxy)-, methyl ester, (Z)-
• CAS NO: 88018-07-9
• Molecular Formula: C12H12O4
• Molecular Weight: 220.225
• Mol File: 88018-07-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 4-(2-formylphenoxy)-, methyl ester, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 4-(2-formylphenoxy)-, methyl ester, (Z)-(88018-07-9)
• EPA Substance Registry System: 2-Butenoic acid, 4-(2-formylphenoxy)-, methyl ester, (Z)-(88018-07-9)

Safety Data

• Hazardous Substances Data: 88018-07-9(Hazardous Substances Data)

Upstream product

• 3052-50-4 monomethyl maleate 
• 925230-65-5 methyl (Z)-4-hydroxy-but-2-enoate 
• 89-95-2 2-methyl-benzyl alcohol 
• 56699-18-4 cis-4-bromo-2-butenoic acid methyl ester 
• 1117-71-1 methyl 4-bromocrotonate 
• 90-02-8 salicylaldehyde 
• 77733-81-4 (2E)-4-<2-(3-Cyan-trans-3-phenyl-2-oxiranyl)phenoxy>-2-butensaeure-methylester 

Downstream Products

• 1181664-48-1 C₁₆H₁₈O₆ 

Relevant articles and documents

SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS

Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.

PPh3-mediated intramolecular conjugation of alkyl halides with electron-deficient olefins: Facile synthesis of chromans and relevant analogues

With the mediation of phosphine, the direct intramolecular coupling of two electrophiles-alkyl halides with electron-deficient olefins-has been successfully realized in an intramolecular conjugate addition manner. The reaction provides a new approach for

Microwave-assisted solvent-free intramolecular 1,3-dipolar cycloaddition reactions leading to hexahydrochromeno[4,3-b]pyrroles: scope and limitations

We report the microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles. Intramolecular 1,3-dipolar cycloadditions proceed under these conditions within 15-40 min in 16-84% yields. An influence of the microwave irradiation upon various [3+2] cycloaddition reaction intermediates was studied. Additionally, a scope and limitations of these reactions including an influence of the dipolarophile geometry upon the cycloaddition selectivity and steric demands of the dipole upon its reactivity were also disclosed. These observations led us to postulate a preferable transition state of the reaction. Finally, an influence of the microwave irradiation to the isomerization of activated olefins was also described.