88083-88-9

Basic information

• Product Name: 6-ethyl-2-phenyl-2H-pyran-4(3H)-one
• Synonyms: 6-ethyl-2-phenyl-2H-pyran-4(3H)-one
• CAS NO: 88083-88-9
• Molecular Weight: 202.253
• Mol File: 88083-88-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-ethyl-2-phenyl-2H-pyran-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-ethyl-2-phenyl-2H-pyran-4(3H)-one(88083-88-9)
• EPA Substance Registry System: 6-ethyl-2-phenyl-2H-pyran-4(3H)-one(88083-88-9)

Safety Data

• Hazardous Substances Data: 88083-88-9(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 911294-25-2 1-hydroxy-1-phenylhept-4-yn-3-one 
• 140-88-5 ethyl acrylate 
• 3002-24-2 hexane-2,4-dione 

Relevant articles and documents

Pd(II)-catalyzed cascade Wacker-Heck reaction: Chemoselective coupling of two electron-deficient reactants

A novel palladium(II)-catalyzed oxy-carbopalladation process was developed allowing for the orchestrated union of hydroxyynones with ethyl acrylate, two electron-deficient reactants. With β-hydroxy ynones, this cascade Wacker-Heck process gave access to highly functionalized tri- or tetrasubstituted dihydropyranones featuring an unusual dienic system. For diastereomerically pure and for enantioenriched β-hydroxyynones, these reactions proceed without affecting the stereochemical integrity of the existing stereocenters. In addition, tetrasubstituted furanones can be prepared when α-hydroxyynones and ethyl acrylate are used as starting materials. The dihydropyranones and furanones obtained upon cyclization are novel compounds, but structurally related carbohydrate derivatives featuring a similar dienic system have been used as starting materials for the construction of polyannulated products, suggesting that these cascade Pd(II)-mediated oxidative heterocyclizations are of value for various synthetic applications.