88115-32-6Relevant articles and documents
Retro Aza Diels-Alder Reactions of 2-Azanorbornenes: Improved Methods for the Unmasking of Primary Amines
Grieco, Paul A.,Clark, Jerry D.
, p. 2271 - 2272 (1990)
The unmasking of primary amines via the heterocycloreversion of N-alkyl-2-azanorbornenes can be catalyzed by either copper(II) or a sulfonic acid based ion exchange resin which obviates the necessity of employing a reactive dienophile to trap the cyclopentadiene as it is produced.
Discovery of N1-(6-Chloroimidazo[2,1-b][1,3]-thiazole-5- sulfonyl)tryptamine as a potent, selective, and orally active 5-HT6 receptor agonist
Cole, Derek C.,Stock, Joseph R.,Lennox, William J.,Bernotas, Ronald C.,Ellingboe, John W.,Boikess, Steve,Coupet, Joseph,Smith, Deborah L.,Leung, Louis,Zhang, Guo-Ming,Feng, Xidong,Kelly, Michael F.,Galante, Rocco,Huang, Pingzhong,Dawson, Lee A.,Marquis, Karen,Rosenzweig-Lipson, Sharon,Beyer, Chad E.,Schechter, Lee E.
, p. 5535 - 5538 (2008/03/15)
N1-Arylsulfonyltryptamines have been identified as 5-HT 6 receptor ligands. In particular, N1(6-chloroimidazo[2,1- b][1,3]thiazole-5-sulfonyl)tryptamine (11q) is a high affinity, potent full agonist (5-HT6 Ksub