88123-64-2

Basic information

• Product Name: 5,6,7,8,9,10-hexahydro-2,4-diphenyl-cycloocta[d]pyrimidine
• CAS NO: 88123-64-2
• Molecular Weight: 314.43
• Mol File: 88123-64-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,6,7,8,9,10-hexahydro-2,4-diphenyl-cycloocta[d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8,9,10-hexahydro-2,4-diphenyl-cycloocta[d]pyrimidine(88123-64-2)
• EPA Substance Registry System: 5,6,7,8,9,10-hexahydro-2,4-diphenyl-cycloocta[d]pyrimidine(88123-64-2)

Safety Data

• Hazardous Substances Data: 88123-64-2(Hazardous Substances Data)

Upstream product

• 696-71-9 cyclooctanol 
• 1670-14-0 benzamidine monohydrochloride 
• 100-51-6 benzyl alcohol 
• 1781-78-8 cyclooctyne 
• 100-47-0 benzonitrile 

Relevant articles and documents

Synthesis of Pyridines, Quinolines, and Pyrimidines via Acceptorless Dehydrogenative Coupling Catalyzed by a Simple Bidentate P^ N Ligand Supported Ru Complex

A ruthenium hydrido chloride complex (1) supported by a simple, heteroleptic bidentate P^N ligand (L1) containing a diarylphosphine and a benzannulated phenanthridine donor arm is reported. In the presence of base, complex 1 catalyzes multicomponent reactions using alcohol precursors to produce structurally diverse molecules including pyridines, quinolines, and pyrimidines via acceptorless dehydrogenative coupling pathways. Notably, L1 does not bear readily (de)protonated Br?nsted acidic or basic groups common to transition metal catalysts capable of these sorts of transformations, suggesting metal-ligand cooperativity does not play a significant role in the catalytic reactivity of 1. A rare example of an η2-aldehyde adduct of ruthenium was isolated and structurally characterized, and its role in acceptorless dehydrogenative coupling reactions is discussed.