881295-84-7

Basic information

• Product Name: 6,7-dimethoxy-3-phenylquinazolin-4(3H)-one
• CAS NO: 881295-84-7
• Molecular Weight: 282.299
• Mol File: 881295-84-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6,7-dimethoxy-3-phenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-3-phenylquinazolin-4(3H)-one(881295-84-7)
• EPA Substance Registry System: 6,7-dimethoxy-3-phenylquinazolin-4(3H)-one(881295-84-7)

Safety Data

• Hazardous Substances Data: 881295-84-7(Hazardous Substances Data)

Upstream product

• 1202401-25-9 2-iodo-4,5-dimethoxy-N-phenylbenzamide 
• 107-11-9 1-amino-2-propene 
• 13794-72-4 3H-6,7-dimethoxyquinazolin-4-one 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Synthesis of 2,3-Disubstituted Quinazolinone Derivatives through Copper Catalyzed C-H Amidation Reactions

The synthesis of quinazolinone derivatives was achieved from 2-iodobenzamide derivatives and various benzylamines, allylamine, and cinnamylamine derivatives through a one-pot copper-catalyzed reaction. In this reaction, the amine component (benzylamine/allylamine/cinnamylamine) is N-arylated with 2-iodobenzamide derivatives through Ullman coupling, followed by an intramolecular C-H amidation in the presence of copper catalyst. Copper-catalyzed tandem-Ullman N-alkylation and intramolecular C-H amidation reaction protocol for the synthesis of 2-phenylquinazolinone and quinazolinone derivatives from N-substituted 2-iodo-benzamides and benzylamines, allyl, and cinnamylamine is achieved.