88154-77-2 Usage
Description
(5R)-5-Methyl-2-(phenylsulfinyl)-cyclohexanone, with the CAS number 88154-77-2, is an organic compound characterized by its chiral center at the 5-position and a phenylsulfinyl group at the 2-position. It exists as a gel, indicating its potential for use in various applications due to its physical state.
Uses
Used in Organic Synthesis:
(5R)-5-Methyl-2-(phenylsulfinyl)-cyclohexanone is used as a key intermediate in organic synthesis for the production of various pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure allows for selective reactions and transformations, making it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (5R)-5-Methyl-2-(phenylsulfinyl)-cyclohexanone is used as a chiral synthon for the development of enantiomerically pure drugs. Its presence of a chiral center and a phenylsulfinyl group provides opportunities for asymmetric synthesis and the creation of novel bioactive compounds with potential therapeutic applications.
Used in Agrochemical Industry:
(5R)-5-Methyl-2-(phenylsulfinyl)-cyclohexanone is also utilized in the agrochemical industry as a precursor for the synthesis of chiral pesticides and other agrochemicals. Its ability to be selectively modified and functionalized makes it an attractive candidate for the development of new and improved agrochemical products.
Used in Specialty Chemicals:
In the specialty chemicals sector, (5R)-5-Methyl-2-(phenylsulfinyl)-cyclohexanone is employed as a versatile building block for the synthesis of chiral compounds with specific applications in various industries, such as fragrances, flavors, and materials science. Its unique properties and reactivity contribute to the creation of high-value specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 88154-77-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,1,5 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88154-77:
(7*8)+(6*8)+(5*1)+(4*5)+(3*4)+(2*7)+(1*7)=162
162 % 10 = 2
So 88154-77-2 is a valid CAS Registry Number.
88154-77-2Relevant articles and documents
Bioinspired Diversification Approach Toward the Total Synthesis of Lycodine-Type Alkaloids
Haley, Hannah M. S.,Payer, Stefan E.,Papidocha, Sven M.,Clemens, Simon,Nyenhuis, Jonathan,Sarpong, Richmond
, p. 4732 - 4740 (2021/04/07)
Nitrogen heterocycles (azacycles) are common structural motifs in numerous pharmaceuticals, agrochemicals, and natural products. Many powerful methods have been developed and continue to be advanced for the selective installation and modification of nitrogen heterocycles through C-H functionalization and C-C cleavage approaches, revealing new strategies for the synthesis of targets containing these structural entities. Here, we report the first total syntheses of the lycodine-type Lycopodium alkaloids casuarinine H, lycoplatyrine B, lycoplatyrine A, and lycopladine F as well as the total synthesis of 8,15-dihydrohuperzine A through bioinspired late-stage diversification of a readily accessible common precursor, N-desmethyl-β-obscurine. Key steps in the syntheses include oxidative C-C bond cleavage of a piperidine ring in the core structure of the obscurine intermediate and site-selective C-H borylation of a pyridine nucleus to enable cross-coupling reactions.
Efforts toward the synthesis of (+)-Lyconadin A
Karella, Satish,Raghavan, Sadagopan
, (2020/08/10)
Abstract: Synthetic efforts toward the synthesis of (+)-lyconadin A are described. B-Alkyl Suzuki coupling is utilized for combining 2-iodo cyclohexenone with the piperidine subunit. The piperidine subunit is derived from 5-bromo-3-nicotinic acid, and iod
Total synthesis of (+)-fawcettidine
Kozak, Jennifer A.,Dake, Gregory R.
scheme or table, p. 4221 - 4223 (2009/03/11)
(Chemical Equation Presented) Alkaloids alchemy: A synthesis of the Lycopodium alkaloid (+)-fawcettidine (see structure) has been developed which requires 16 steps from (R)-(+)-pulegone as the chiral starting material. Key steps include a platinum(II)-cat
