881673-83-2

Basic information

• Product Name: 1-[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine
• Synonyms: 1-[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine
• CAS NO: 881673-83-2
• Molecular Weight: 329.217
• Mol File: 881673-83-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine(881673-83-2)
• EPA Substance Registry System: 1-[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine(881673-83-2)

Safety Data

• Hazardous Substances Data: 881673-83-2(Hazardous Substances Data)

Usage

Structure

Contains a pyrrole ring, a bromine atom, a sulfonylphenyl group, and a methylamino group

Type

Synthetic chemical compound

Application

Used in chemical research and drug development as a potential pharmaceutical intermediate

Biological activity

May have biological activity, but specific functions and applications are still under investigation

Potential uses

Fields of medicine, pharmacology, and chemistry

Investigation status

As a novel chemical compound, its specific functions and applications are still under investigation

Upstream product

• 881673-82-1 5-bromo-1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde 
• 593-51-1 methylamine hydrochloride 
• 98-09-9 benzenesulfonyl chloride 
• 16420-39-6 methyl 5-bromo-1H-pyrrole-3-carboxylate 
• 881673-81-0 [5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol 
• 881673-80-9 methyl 5-bromo-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate 
• 2703-17-5 methyl 1H-pyrrole-3-carboxylate 

Downstream Products

• 881673-84-3 tert-butyl {[5-bromo-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-methyl}methylcarbamate 
• 881673-86-5 tert-butyl methyl{[5-phenyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methyl}carbamate 
• 881678-78-0 N-methyl-1-[5-phenyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-methanamine hydrochloride 
• 881673-85-4 tert-butyl methyl{[1-(phenylsulfonyl)-5-(3-thienyl)-1H-pyrrol-3-yl]methyl}carbamate 

Relevant articles and documents

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

Acid secretion inhibitor

The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.