88186-34-9

Basic information

• Product Name: Oxazole, 4,5-dihydro-2-(2-nitrophenyl)-
• CAS NO: 88186-34-9
• Molecular Formula: C9H8N2O3
• Molecular Weight: 192.174
• Mol File: 88186-34-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 52-53 °C
• Boiling Point: 175 °C(Press: 5 Torr)
• Density: 1.40±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Oxazole, 4,5-dihydro-2-(2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 4,5-dihydro-2-(2-nitrophenyl)-(88186-34-9)
• EPA Substance Registry System: Oxazole, 4,5-dihydro-2-(2-nitrophenyl)-(88186-34-9)

Safety Data

• Hazardous Substances Data: 88186-34-9(Hazardous Substances Data)

Upstream product

• 84946-21-4 N-(2-chloroethyl)-2-nitrobenzamide 
• 141-43-5 ethanolamine 
• 552-89-6 2-nitro-benzaldehyde 
• 610-14-0 2-nitrobenzyl chloride 
• 63004-24-0 2-nitro-benzoic acid-(2-bromo-ethylamide) 

Downstream Products

• 3416-93-1 2-(4,5-Dihydro-1,3-oxazol-2-yl)aniline 
• 3416-96-4 N-[2-(4,5-dihydro-thiazol-2-yl)-phenyl]-toluene-4-sulfonamide 
• 3770-67-0 N-[2-(4,5-dihydrooxazol-2-yl)phenyl]-4-methylbenzenesulfonamide 
• 552-89-6 2-nitro-benzaldehyde 

Relevant articles and documents

Poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide), N,N,N′,N′- tetrabromobenzene-1, 3-disulfonamide as new efficient reagents for conversion of alcohols to THP ethers and aldehydes to oxazoline compounds

This paper is concerned with an easy preparation of THP ethers from primary, secondary and tertiary alcohols and oxazoline compounds from various aldehydes using poly(N-bromo-N-ethyl-benzene-1,3-disulfonamide), N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide [TBBDA] as new and efficient reagents under ambient conditions without over-oxidation.

A convenient synthesis of oxazolines and imidazolines from aromatic aldehydes with pyridinium hydrobromide perbromide in water

Various 2-oxazolines were prepared from aromatic aldehydes and 2-aminoethanol with pyridinium hydrobromide perbromide in water at room temperature. 2-Imidazolines were also obtained in good yields from aromatic aldehydes and ethylenediamine under the same reaction conditions. Georg Thieme Verlag Stuttgart.