882033-33-2 Usage
Structure
A heterocyclic organic compound containing a pyridine ring fused to a pyrrole ring.
Substitution
Methoxy groups attached at the 5th and 6th positions.
Potential applications
Medicinal chemistry, particularly in the development of new pharmaceuticals.
Importance
The pyrrolopyridine core makes it a valuable building block for the synthesis of biologically active molecules and pharmaceutical drugs.
Uniqueness
Unique chemical structure and properties make it an important research target for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 882033-33-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,2,0,3 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 882033-33:
(8*8)+(7*8)+(6*2)+(5*0)+(4*3)+(3*3)+(2*3)+(1*3)=162
162 % 10 = 2
So 882033-33-2 is a valid CAS Registry Number.
882033-33-2Relevant articles and documents
Design of potent IGF1-R inhibitors related to bis-azaindoles
Nemecek, Conception,Metz, William A.,Wentzler, Sylvie,Ding, Fa-Xiang,Venot, Corinne,Souaille, Catherine,Dagallier, Anne,Maignan, Sebastien,Guilloteau, Jean-Pierre,Bernard, Francois,Henry, Alain,Grapinet, Sandrine,Lesuisse, Dominique
, p. 100 - 106 (2011/03/19)
From an azaindole lead, identified in high throughput screen, a series of potent bis-azaindole inhibitors of IGF1-R have been synthesized using rational drug design and SAR based on a in silico binding mode hypothesis. Although the resulting compounds produced the expected improved potency, the model was not validated by the co-crystallization experiments with IGF1-R.
